3127 Introduction: We have developed a synthetic peptide designated 124 I-p5+ 14, for
PET/CT imaging of patients with systemic amyloidosis. Based on positive preclinical data …

172 Introduction: Systemic amyloidosis is characterized by the deposition of fibrillar amyloid
deposits in abdominothoracic organs, notably the heart, liver, spleen and kidneys, leading to …

Purpose Accurate diagnosis of amyloidosis remains a significant clinical challenge and
unmet need for patients. The amyloid-reactive peptide p5+ 14 radiolabeled with iodine-124 …

There are at least 20 distinct types of systemic amyloidosis, all of which result in the organ-
compromising accumulation of extracellular amyloid deposits. Amyloidosis is challenging to …

Background: Immunoglobulin light chain-associated (AL) amyloidosis is associated with the
deposition of fibrils in abdominothoracic organs, notably the heart, liver, spleen and kidneys …

Background: Systemic immunoglobulin light chain-associated amyloidosis (AL) is a rare
disorder associated with plasma cell dyscrasias and the production of monoclonal free light …

83 Objectives Amyloidosis, a pathology characterized by the deposition of protein fibrils and
heparan sulfate proteoglycans in the brain and other organs, is associated with Alzheimer's …

1534 Objectives Visceral amyloid deposits are found in patients with rheumatoid arthritis,
multiple myeloma, and type 2 diabetes. The development of amyloid in these cases …

1834 Objectives: Preliminary pharmacokinetic study of a bispecific peptide for pretargeting
immunotherapy of amyloidosis using PreClinical SPECT/CT Amyloid deposition in …

Purpose Systemic peripheral amyloidosis is a rare disease in which misfolded proteins
deposit in various organs. We have previously developed I-124 labeled peptide p5+ 14 as a …