When plateau concentrations of FDG are achieved in tissues with low con centration of
glucose-6-phosphatase, images oftotal †8Fradioactivity reflect relative rates of glycolysis …

The rate constants K* 1and k* 2refer to forward and reverse capillary trans port of FDG, while
k* 3 and k* 4 refer to phosphorylation of FDG and de phosphorylation of FDG-6-P04, re …

The enhanced rate of glucose utilization by tumor cells has been exploited in the imaging of
tumors using the radiolabelled glucose analogue fluoro-2-deoxy-D-glucose (FDG)[1], which …

Conclusion: These results indicate that the observed tumor tissue uptake of 18FDG,
corrected for blood 18FDGactivity and glucose concentration, can reliably predict glucose …

Positron emission tomography using the glucose analog fluorine-18 fluorodeoxyglucose
(FDG-PET) provides a unique means of non-invasive assessment of tumor metabolism …

A rapidly emerging clinical application of positron emission tomography (PET) is the
detection and staging of cancer with the glucose analogue tracer 2-[fluorine-18] fluoro-2 …

The high diagnostic accuracy of FDG-PET and PET/CT has been well documented for
several neoplasms, with a consequent rapid increase in the utilization and acceptance of …

99.0% ±0.4% andthespecificactivityabout2 Ci/@ imolatthe end ofthe synthesis. The first
PET-FDG study was performed in the fasting state. After fastingovernight, the patients …

FDG PET imaging has been applied for about a decade. It is generally accepted that
imaging the metabolic activity of tumor tissue provides more sensitive and more specific …

The use of FDG-PET imaging in tumour detection is now well established. Many studies
have suggested that changes in the uptake of FDG predict tumour response to therapy and …