Combined PARP1-Targeted Nuclear Contrast and Reflectance Contrast Enhance Confocal Microscopic Detection of Basal Cell Carcinoma

A Sahu, J Cordero, X Wu, S Kossatz… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Reflectance confocal microscopy (RCM) with endogenous backscattered contrast can
noninvasively image basal cell carcinomas (BCCs) in skin. However, BCCs present with …

[HTML][HTML] Reflectance confocal microscopy and dermoscopy for in vivo, non-invasive skin imaging of superficial basal cell carcinoma

MA Ghita, C Caruntu, AE Rosca… - Oncology …, 2016 - spandidos-publications.com
Superficial basal cell carcinoma (sBCC) is the second most frequent histological type of
basal cell carcinoma (BCC), usually requiring a skin biopsy to confirm the diagnosis. It …

PARP1: a potential molecular marker to identify cancer during colposcopy procedures

PD de Souza França, N Guru… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Despite efforts in prevention, cervical cancer still presents with a high worldwide incidence
and remains a great problem in public health, especially in low-income countries. Screening …

A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer

P Demetrio de Souza Franca, S Kossatz… - European journal of …, 2021 - Springer
Background Visual inspection and biopsy is the current standard of care for oral cancer
diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically …

High-contrast mapping of basal cell carcinomas

AN Yaroslavsky, R Patel, E Salomatina, C Li, C Lin… - Optics letters, 2012 - opg.optica.org
Because of low optical contrast in the visible spectral range, accurate detection of basal cell
carcinomas (BCC) remains a challenging problem. In this letter, we experimentally …

PARP1 as a biomarker for early detection and intraoperative tumor delineation in epithelial cancers–first-in-human results

S Kossatz, G Pirovano, PD De Souza França… - BioRxiv, 2019 - biorxiv.org
Major determining factors for survival of patients with oral, oropharyngeal, and esophageal
cancer are early detection, the quality of surgical margins, and the contemporaneous …

Detection of residual basal cell carcinoma by in vivo confocal microscopy

DE Marra, A Torres, CF Schanbacher… - Dermatologic …, 2005 - journals.lww.com
Detection of Residual Basal Cell Carcinoma by In Vivo Confoc... : Dermatologic Surgery
Detection of Residual Basal Cell Carcinoma by In Vivo Confocal Microscopy : Dermatologic …

Should reflectance confocal microscopy be the gold standard for basal cell carcinoma diagnosis?

S González - Imaging in Medicine, 2013 - search.proquest.com
Reflectance confocal microscopy (RCM) is a novel application of scanning confocal
microscopy that generates high spatiotemporal resolution images of the superficial layers of …

Detection and delineation of oral cancer with a PARP1-targeted optical imaging agent

S Kossatz, W Weber, T Reiner - Molecular imaging, 2017 - journals.sagepub.com
More sensitive and specific methods for early detection are imperative to improve survival
rates in oral cancer. However, oral cancer detection is still largely based on visual …

[HTML][HTML] In vivo reflectance confocal microscopy of wounds: Feasibility of intraoperative basal cell carcinoma margin assessment

V Shavlokhova, M Vollmer, A Vollmer… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background In vivo reflectance confocal microscopy (RCM) is well established in non-
melanoma skin cancer detection and screening. However, there is no sufficient validation …