This Month in JNM Page 1 Somatostatin receptor theranostics: Park and colleagues provide an
overview of the current role of SSTR PET in neuroendocrine neoplasms, including selection of …

Twenty-two years after the identification of somatostatin, an understanding of its biology
remains a challenge and its therapeutic potential has not, as yet, been fully exploited. In the …

There is considerable controversy about the classification and nomenclature of somatostatin
receptors. To date, five distinct receptor genes have been cloned and named …

Somatostatin is a regulatory peptide involved in a wide variety of biological functions
throughout the body. A key physiological question, as well as the challenge to developing …

In 1972, Brazeau et al. isolated somatostatin (somatotropin release-inhibiting factor, SRIF), a
cyclic polypeptide with two biologically active isoforms (SRIF-14 and SRIF-28). This event …

S. Reichlin (ed.), Somatostatin © Springer Science+Business Media New York 1987 Page 1 9
SOMATOSTATIN RECEPTOR: EVIDENCE FOR FUNCTIONAL AND STRUCTURAL …

Somatostatin receptors expressed on tumor cells form the rationale for somatostatin analog
treatment of patients with somatostatin receptor-positive neuroendocrine tumors …

The discovery of somatostatin has transformed our concepts of the physiol ogy and
pathophysiology of endocrine and non-endocrine organs, and stimu lated worldwide basic …

One might call the peptide an inhibitory tissue (growth) factor, which mainly prevents local
overreaction from a multitude of stimulatory factors. Long-term administration of somatostatin …

The five known somatostatin receptors serve unique biological roles by virtue of their tissue‐
specific expression and particular biochemical properties. However, the function of any …