Longitudinal amyloid and tau PET imaging in Alzheimer's disease: A systematic review of methodologies and factors affecting quantification
Deposition of amyloid and tau pathology can be quantified in vivo using positron emission
tomography (PET). Accurate longitudinal measurements of accumulation from these images …
tomography (PET). Accurate longitudinal measurements of accumulation from these images …
[HTML][HTML] Software compatibility analysis for quantitative measures of [18F]flutemetamol amyloid PET burden in mild cognitive impairment
HG Pemberton, C Buckley, M Battle, A Bollack, V Patel… - EJNMMI research, 2023 - Springer
Rationale Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in
Alzheimer's disease pathogenesis. In clinical practice, trained readers will visually …
Alzheimer's disease pathogenesis. In clinical practice, trained readers will visually …
Quantitative Brain Amyloid PET
WJ Jagust, VS Mattay, DM Krainak… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Since the development of amyloid tracers for PET imaging, there has been interest in
quantifying amyloid burden in the brains of patients with Alzheimer disease. Quantitative …
quantifying amyloid burden in the brains of patients with Alzheimer disease. Quantitative …
Amyloid brain-dedicated PET images can diagnose Alzheimer's pathology with Centiloid Scale
MT Gandia-Ferrero, I Torres-Espallardo… - Physica Medica, 2024 - Elsevier
Purpose To evaluate whether the Centiloid Scale may be used to diagnose Alzheimer's
Disease (AD) pathology effectively with the only use of amyloid PET imaging modality from a …
Disease (AD) pathology effectively with the only use of amyloid PET imaging modality from a …
[HTML][HTML] Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
M Shekari, EE Verwer, M Yaqub, M Daamen… - EJNMMI physics, 2023 - Springer
Background Image harmonization has been proposed to minimize heterogeneity in brain
PET scans acquired in multi-center studies. However, standard validated methods and …
PET scans acquired in multi-center studies. However, standard validated methods and …
Investigating reliable amyloid accumulation in Centiloids: Results from the AMYPAD Prognostic and Natural History Study
INTRODUCTION To support clinical trial designs focused on early interventions, our study
determined reliable early amyloid‐β (Aβ) accumulation based on Centiloids (CL) in pre …
determined reliable early amyloid‐β (Aβ) accumulation based on Centiloids (CL) in pre …