Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177Lu‐PSMA‐617 in prostate cancer patients
H Siebinga, BM Privé, SMB Peters… - CPT …, 2023 - Wiley Online Library
Studies to evaluate and optimize [177Lu] Lu‐PSMA treatment focus primarily on individual
patient data. A population pharmacokinetic (PK) dosimetry model was developed to explore …
patient data. A population pharmacokinetic (PK) dosimetry model was developed to explore …
[HTML][HTML] A proof of principle study using radiopharmaceuticals to quantify and localize container-content interactions in medical syringes
C Dupire, P Chennell, B Pereira, N Courtiol, S Buj… - Scientific Reports, 2023 - nature.com
The sorption of drugs onto their contents is a known phenomenon that is difficult to analyse
precisely. The purpose of this study was to present a non-invasive method for locating and …
precisely. The purpose of this study was to present a non-invasive method for locating and …
Determining the optimal pharmacokinetic modelling and simplified quantification method of [18F]AlF-P16-093 for patients with primary prostate cancer (PPCa)
R Zhao, Z Xia, M Ke, J Lv, H Zhong, Y He, D Gu… - European Journal of …, 2024 - Springer
Purpose This paper discusses the optimization of pharmacokinetic modelling and alternate
simplified quantification method for [18F] AlF-P16-093, a novel tracer for in vivo imaging of …
simplified quantification method for [18F] AlF-P16-093, a novel tracer for in vivo imaging of …
[HTML][HTML] First-in-human validation of a DROP-IN β-probe for robotic radioguided surgery: defining optimal signal-to-background discrimination algorithm
F Collamati, S Morganti, MN van Oosterom… - European Journal of …, 2024 - Springer
Purpose In radioguided surgery (RGS), radiopharmaceuticals are used to generate
preoperative roadmaps (eg, PET/CT) and to facilitate intraoperative tracing of tracer avid …
preoperative roadmaps (eg, PET/CT) and to facilitate intraoperative tracing of tracer avid …
[HTML][HTML] Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling
H Siebinga, JJMA Hendrikx, ADR Huitema… - EJNMMI research, 2023 - Springer
Background Folate intake might reduce [68Ga] Ga-PSMA-11 uptake in tissues due to a
competitive binding to the PSMA receptor. For diagnostic imaging, this could impact decision …
competitive binding to the PSMA receptor. For diagnostic imaging, this could impact decision …
[HTML][HTML] Predicting [177Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [68Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological …
H Siebinga, BJ de Wit-van der Veen, JH Beijnen… - EJNMMI physics, 2023 - Springer
Abstract Background Prediction of [177Lu] Lu-HA-DOTATATE kidney and tumor uptake
based on diagnostic [68Ga] Ga-HA-DOTATATE imaging would be a crucial step for …
based on diagnostic [68Ga] Ga-HA-DOTATATE imaging would be a crucial step for …
[PDF][PDF] Predicting [177 Lu] Lu-HA-DOTATATE kidney and tumor accumulation based on [68 Ga] Ga-HA-DOTATATE diagnostic imaging using semi-physiological …
TPC Dorlo, ADR Huitema, JJMA Hendrikx - 2023 - ejnmmiphys.springeropen.com
Abstract Background: Prediction of [177Lu] Lu‑HA‑DOTATATE kidney and tumor uptake
based on diagnostic [68Ga] Ga‑HA‑DOTATATE imaging would be a crucial step for …
based on diagnostic [68Ga] Ga‑HA‑DOTATATE imaging would be a crucial step for …
[PDF][PDF] Wetenschappelijke vergadering NVNG: Veiligheid voor alles
CWOV NVNG - SPECT/CT als alternatief voor …, 2023 - tijdschriftvoornucleairegeneeskunde …
Materials and Methods Five patients with non-small-cell lung cancer (NSCLC) who will
receive 25 fractions radiotherapy with concurrent low-dose cisplatin were included. Patients …
receive 25 fractions radiotherapy with concurrent low-dose cisplatin were included. Patients …