[HTML][HTML] Recent advances in locoregional therapy of hepatocellular carcinoma

A Podlasek, M Abdulla, D Broering, K Bzeizi - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the fifth most common cancer
worldwide and the second most common oncological reason for death. Liver resection and …

[HTML][HTML] Hepatocellular Carcinoma cells: activity of Amygdalin and Sorafenib in Targeting AMPK/mTOR and BCL-2 for anti-angiogenesis and apoptosis cell death

T El-Sewedy, AF Salama, AE Mohamed… - … Medicine and Therapies, 2023 - Springer
Abstract Background Sorafenib (Sor) is the only approved multikinase inhibitor indicated for
the treatment of HCC. Previous studies have shown that amygdalin (Amy) possesses …

Polymer composite microspheres loading 177Lu radionuclide for interventional radioembolization therapy and real-time SPECT imaging of hepatic cancer

L Xiao, Y Li, R Geng, L Chen, P Yang, M Li… - Biomaterials …, 2023 - spj.science.org
Background Transarterial radioembolization (TARE) with 90Y-labeled glass and resin
microspheres is one of the primary treatment strategies for advanced-stage primary and …

[HTML][HTML] Nutritional status in patients with hepatocellular carcinoma: Potential relevance for clinical outcome

AM van Dijk, BJP Coppens, MA van Beers… - European Journal of …, 2022 - Elsevier
Background Impaired nutritional status is a risk factor for unfavorable outcome in cirrhosis.
Methods In this prospective cohort study in hepatocellular carcinoma patients referred for …

[HTML][HTML] Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol

D Andel, MGEH Lam, J de Bruijne, MLJ Smits… - BMC cancer, 2023 - Springer
Background High dose unilobar radioembolization (also termed 'radiation lobectomy')—the
transarterial unilobar infusion of radioactive microspheres as a means of controlling tumour …

[HTML][HTML] Clinical Results of Transarterial Radioembolization (TARE) with Holmium-166 Microspheres in the Multidisciplinary Oncologic Treatment of Patients with …

R Drescher, A Köhler, P Seifert, R Aschenbach, T Ernst… - Biomedicines, 2023 - mdpi.com
Holmium-166 microspheres are used for the transarterial radioembolization (TARE)
treatment of primary and secondary liver cancers. In this study, its efficacy regarding local …

[HTML][HTML] Intraprocedural MRI-based dosimetry during transarterial radioembolization of liver tumours with holmium-166 microspheres (EMERITUS-1): a phase I trial …

J Roosen, LEL Westlund Gotby, MJ Arntz… - European Journal of …, 2022 - Springer
Purpose Transarterial radioembolization (TARE) is a treatment for liver tumours based on
injection of radioactive microspheres in the hepatic arterial system. It is crucial to achieve a …

[HTML][HTML] Adjuvant holmium-166 radioembolization after radiofrequency ablation in early-stage hepatocellular carcinoma patients: a dose-finding study (HORA EST …

P Hendriks, DDD Rietbergen, AR van Erkel… - European Journal of …, 2024 - Springer
Purpose The aim of this study was to investigate the biodistribution of (super-) selective trans-
arterial radioembolization (TARE) with holmium-166 microspheres (166Ho-MS), when …

MIDOS: a novel stochastic model towards a treatment planning system for microsphere dosimetry in liver tumors

C Huesa-Berral, JD Withrow, RJ Dawson… - European Journal of …, 2023 - Springer
Purpose Transarterial radioembolization (TARE) procedures treat liver tumors by injecting
radioactive microspheres into the hepatic artery. Currently, there is a critical need to optimize …

[HTML][HTML] Holmium-166 Transarterial Radioembolization for the Treatment of Intrahepatic Cholangiocarcinoma: A Case Series

S Vermeulen, K De Keukeleire, N Dorny, I Colle… - Cancers, 2023 - mdpi.com
Simple Summary Intrahepatic cholangiocarcinoma (ICC) is a liver cancer with a poor
prognosis, which is often not resectable at diagnosis. The search for novel effective …