Non-invasive molecular imaging for precision diagnosis of metastatic lymph nodes: opportunities from preclinical to clinical applications

Z Cheng, J Ma, L Yin, L Yu, Z Yuan, B Zhang… - European Journal of …, 2023 - Springer
Lymph node metastasis is an indicator of the invasiveness and aggressiveness of cancer. It
is a vital prognostic factor in clinical staging of the disease and therapeutic decision-making …

[HTML][HTML] Multispectral optoacoustic tomography for in vivo detection of lymph node metastases in oral cancer patients using an EGFR-targeted contrast agent and …

J Vonk, J Kukačka, PJ Steinkamp, JG De Wit… - Photoacoustics, 2022 - Elsevier
Oral cancer patients undergo diagnostic surgeries to detect occult lymph node metastases
missed by preoperative structural imaging techniques. Reducing these invasive procedures …

A guideline for clinicians performing clinical studies with fluorescence imaging

W Heeman, J Vonk, V Ntziachristos… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Fluorescence imaging is an emerging imaging technique that has shown many benefits for
clinical care. Currently, the field is in rapid clinical translation, and an unprecedented …

Red/NIR emission carbonized polymer dots based on citric acid-benzoylurea and their application in lymph nodes imaging

F Shan, T Zhang, C Liao, X Yue, J Zhang, L Yan… - Chinese Chemical …, 2023 - Elsevier
Identification of lymph nodes (LNs) is critical for studies of the structure, the role in disease
development, and the efficacy of disease treatment. Carbonized polymer dots (CPDs) are …

89Zr-panitumumab Combined With 18F-FDG PET Improves Detection and Staging of Head and Neck Squamous Cell Carcinoma

YJ Lee, NS van den Berg, H Duan, EC Azevedo… - Clinical Cancer …, 2022 - AACR
Purpose: Determine the safety and specificity of a tumor-targeted radiotracer (89Zr-pan) in
combination with 18F-FDG PET/CT to improve diagnostic accuracy in head and neck …

[HTML][HTML] Development of a fibroblast activation protein-targeted PET/NIR dual-modality probe and its application in head and neck cancer

D Li, X Li, J Li, Y Wang, F Tan, X Li - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Purpose: The combination of near-infrared (NIR) and positron emission tomography (PET)
imaging presents an opportunity to utilize the benefits of dual-modality imaging for tumor …

[HTML][HTML] Detection of tumour-targeted IRDye800CW tracer with commercially available laparoscopic surgical systems

DJ Sikkenk, AJ Sterkenburg, I Schmidt, D Gorpas… - Diagnostics, 2023 - mdpi.com
(1) Introduction: Near-infrared fluorescence (NIRF) combined with tumour-targeted tracers,
such as bevacizumab-800CW, could aid surgical decision-making. This study explored the …

How advanced imaging will guide therapeutic strategies for patients with newly diagnosed prostate cancer in the years to come

MGM Schilham, M Rijpkema, T Scheenen, R Hermsen… - European Urology, 2022 - Elsevier
Recent developments in (molecular) imaging technologies have led to significant changes
in diagnostic, staging, and therapeutic processes in prostate cancer (PCa). The recent …

[HTML][HTML] Robot-assisted fluorescent sentinel lymph node identification in early-stage colon cancer

DJ Sikkenk, AJ Sterkenburg, TA Burghgraef, H Akol… - Surgical …, 2023 - Springer
Background Patients with cT1-2 colon cancer (CC) have a 10–20% risk of lymph node
metastases. Sentinel lymph node identification (SLNi) could improve staging and reduce …

[HTML][HTML] How image-guided pathology can improve the detection of lymph node metastases in prostate cancer

MGM Schilham, H Küsters-Vandevelde… - Clinical Nuclear …, 2022 - journals.lww.com
Detection of lymph node (LN) metastases in prostate cancer (PCa) is pivotal for accurate
staging and determining treatment options. To date, the reference standard for nodal staging …