Current status and progress in using radiolabelled PARP-1 inhibitors for imaging PARP-1 expression in tumours

Q Wang, J Zhang - European Journal of Medicinal Chemistry, 2022 - Elsevier
Abstract Poly (ADP-ribose) polymerase-1 (PARP-1) is a key enzyme in the DNA repair
process, and the overexpression of PARP-1 in several tumours makes this enzyme a …

[HTML][HTML] Novel applications of molecular imaging to guide breast cancer therapy

CE Edmonds, SR O'Brien, DA Mankoff, AR Pantel - Cancer Imaging, 2022 - Springer
The goals of precision oncology are to provide targeted drug therapy based on each
individual's specific tumor biology, and to enable the prediction and early assessment of …

The Preparation and Execution of Exploratory Human Studies on Novel 99mTc-Labeled Glucosamine Derivatives Containing Different Phenyl Isonitriles as Promising …

Q Wang, Q Gan, Y Jiang, D Xiao, X Chen… - ACS Pharmacology & …, 2023 - ACS Publications
As the “molecule of the century”, 2-deoxy-2-[18F] fluoro-d-glucose ([18F] FDG) is a
radioactive 18F-labeled glucose derivative with a wide range of applications for positron …

Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74

IK Lee, E Noguera-Ortega, Z Xiao, L Todd… - Clinical Cancer …, 2022 - AACR
Purpose: Despite the success of chimeric antigen receptor (CAR) T-cell therapy against
hematologic malignancies, successful targeting of solid tumors with CAR T cells has been …

[HTML][HTML] Advancements of molecular imaging and radiomics in pancreatic carcinoma

XX Pang, L Xie, WJ Yao, XX Liu, B Pan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Despite the recent progress of medical technology in the diagnosis and treatment of tumors,
pancreatic carcinoma remains one of the most malignant tumors, with extremely poor …

Bench to Bedside Imaging in Brain Metastases: A Road to Precision Oncology

S Shukla, A Karbhari, S Rastogi, U Agarwal, P Rai… - Clinical Radiology, 2024 - Elsevier
Radiology has seen tremendous evolution in the last few decades. At the same time,
oncology has made great strides in diagnosing and treating cancer. Distant metastases of …

Molecular Imaging in Oncology

S Vallabhajosula - Molecular Imaging and Targeted Therapy …, 2023 - Springer
Radioisotope-based molecular imaging (MI) techniques such as PET/CT and SPECT/CT
aim to integrate patient-specific and disease-specific molecular information with traditional …