[HTML][HTML] Lutetium Lu 177 vipivotide tetraxetan: first approval

SJ Keam - Molecular diagnosis & therapy, 2022 - Springer
Lutetium Lu 177 vipivotide tetraxetan (PLUVICTO™, formerly known as 177Lu-PSMA-617)
is a radioligand therapeutic agent that is being developed by Advanced Accelerator …

[HTML][HTML] Radiolabeled PSMA inhibitors

OC Neels, K Kopka, C Liolios, A Afshar-Oromieh - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer remains one of the leading causes of cancer death in men
worldwide. Despite the recent success in the development and clinical application of …

[HTML][HTML] Targeted drug delivery and theranostic strategies in malignant lymphomas

T Etrych, A Braunova, D Zogala, L Lambert… - Cancers, 2022 - mdpi.com
Simple Summary The concept of targeted drug delivery (TDD) represents an innovative and
effective treatment approach, which was developed with an attempt to minimize damage …

[HTML][HTML] Total Tumor Volume on 18F-PSMA-1007 PET as Additional Imaging Biomarker in mCRPC Patients Undergoing PSMA-Targeted Alpha Therapy with 225Ac …

LM Unterrainer, L Beyer, MJ Zacherl, FJ Gildehaus… - Biomedicines, 2022 - mdpi.com
Background: PSMA-based alpha therapy using 225Ac-PSMA-I&T provides treatment for
metastatic castration-resistant prostate cancer (mCRPC), even after the failure of 177Lu …

[PDF][PDF] To scan or not to scan: an unnecessary dilemma for PSMA radioligand therapy

S Srinivas, A Iagaru - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
The recently presented and published results of the VISION phase III study of 177Lu-
PSMA617 for metastatic castrationresistant prostate cancer (1) are indeed one of the …

SNMMI Clinical Trials Network research series for technologists: clinical research primer—use of imaging agents in therapeutic drug development and approval

CD Jeffers, C Lawhn-Heath, RI Butterfield… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The process of bringing a new drug to market is complex and has recently necessitated a
new drug-discovery paradigm for the pharmaceutical industry that is both more efficient and …

Synthesis of tritium-labeled Lu-PSMA-617: Alternative tool for biological evaluation of radiometal-based pharmaceuticals

U Bauder-Wüst, M Schäfer, R Winter, Y Remde… - Applied Radiation and …, 2023 - Elsevier
This project focuses on the generation and evaluation of functional alternatives to radiometal-
based pharmaceuticals supporting basic research and the in vitro developmental phase …

[PDF][PDF] The future of PSMA-targeting 64Cu-radiopharmaceuticals: a short review of recent preclinical research

LA Hasnowo - … студентов и аспирантов: сборник докладов II …, 2022 - earchive.tpu.ru
Abstract Development and testing of prostate-specific membrane antigen (PSMA)-targeting
radionuclide therapy (TRT) for prostate cancer diagnosis and endoradiotherapy have seen …

[PDF][PDF] A VISION of ALSYMPCA

PS Duarte - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Dear sir, I just read the two editorials written by Michael Hofman (1) and by Czernim and
Calais (2) commenting on the use of 177Lu–PSMA-617 therapy in patients with metastatic …

[PDF][PDF] Commercially competitive vendor-agnostic image reconstruction could be a leap forward for PET harmonization

AL Kesner - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
I read with interest the recent publication in JNM titled “A guide to ComBat harmonization of
imaging biomarkers in multicenter studies”(1). The work discussed in the article presents …