16α-18F-fluoro-17β-fluoroestradiol (FES): clinical applications for patients with breast cancer

GA Ulaner - Seminars in Nuclear Medicine, 2022 - Elsevier
Estrogen receptor (ER) is highly expressed in 70%-80% of breast cancers and plays a
central role in prognosis and treatment selection for patients with breast cancer. The gold …

[HTML][HTML] Non-conventional and investigational PET radiotracers for breast cancer: a systematic review

M Balma, V Liberini, M Racca, R Laudicella… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is one of the most common malignancies in women, with high morbidity and
mortality rates. In breast cancer, the use of novel radiopharmaceuticals in nuclear medicine …

Summary: Appropriate use criteria for estrogen receptor–targeted PET imaging with 16α-18F-Fluoro-17β-Fluoroestradiol

GA Ulaner, DA Mankoff, AS Clark… - Journal of Nuclear …, 2023 - Soc Nuclear Med
PET imaging with 16α-18F-fluoro-17β-fluoroestradiol (18F-FES), a radiolabeled form of
estradiol, allows whole-body, noninvasive evaluation of estrogen receptor (ER). 18F-FES is …

Clinical Validity of 16α-[18F]Fluoro-17β-Estradiol Positron Emission Tomography/Computed Tomography to Assess Estrogen Receptor Status in Newly Diagnosed …

JJL van Geel, J Boers, SG Elias… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Determining the estrogen receptor (ER) status is essential in metastatic breast
cancer (MBC) management. Whole-body ER imaging with 16α-[18F] fluoro-17β-estradiol …

[HTML][HTML] Chemotherapy shows a better efficacy than endocrine therapy in metastatic breast cancer patients with a heterogeneous estrogen receptor expression …

Y Xie, X Du, Y Zhao, C Gong, S Hu, S You, S Song… - Cancers, 2022 - mdpi.com
Simple Summary About 10–20% of breast cancer patients have a heterogeneous estrogen
receptor expression. The diagnosis and treatment strategy remains controversial in these …

Incidence and prognostic significance of receptor discordance between primary breast cancer and paired bone metastases

M Lin, Y Jin, H Lv, X Hu, J Zhang - International journal of …, 2023 - Wiley Online Library
ER, PgR and HER‐2 status are the cornerstones of choosing systemic therapy for breast
cancer, but can change during the disease course. Guidelines recommended the biopsy of …

[HTML][HTML] GRPR-targeting radiotheranostics for breast cancer management

A D'Onofrio, S Engelbrecht, T Läppchen… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Breast Cancer (BC) is the most common cancer worldwide and, despite the advancements
made toward early diagnosis and novel treatments, there is an urgent need to reduce its …

Estrogen receptor-targeted and progesterone receptor-targeted PET for patients with breast Cancer

GA Ulaner, AM Fowler, AS Clark, H Linden - PET clinics, 2023 - pet.theclinics.com
Estrogen Receptor-Targeted and Progesterone Receptor-Targeted PET for Patients with Breast
Cancer - PET Clinics Skip to Main Content Advertisement PET Clinics Log in Register Log in …

18F-FES PET/CT for characterization of brain and leptomeningeal metastasis in double primary cancer patient

Y Lee, IR Yoo, S Ha - Clinical Nuclear Medicine, 2022 - journals.lww.com
The clinical value of 16α-18 F-fluoro-17 β-estradiol (18 F-FES) PET in breast cancer has
been widely investigated because it can visualize estrogen receptor–expressing lesions …

18F-Fluoroestradiol (FES) PET/CT: review of current practice and future directions

SR O'Brien, CE Edmonds, D Katz, DA Mankoff… - Clinical and …, 2022 - Springer
Purpose This expert review describes the development and foundational studies of [18F]
fluoroestradiol (18F-FES) in the setting of imaging estrogen receptor (ER)-positive breast …