[HTML][HTML] The evolution of PRRT for the treatment of neuroendocrine tumors; What comes next?

PE Harris, K Zhernosekov - Frontiers in Endocrinology, 2022 - frontiersin.org
Lu-177 has been developed for the treatment of patients with peptide receptor radionuclide
therapy (PRRT). A second generation pure no-carrier-added Lu-177 has a high specific …

Gastric neuroendocrine neoplasms

G Lamberti, F Panzuto, M Pavel, D O'Toole… - Nature Reviews …, 2024 - nature.com
Gastric neuroendocrine neoplasms (gNENs) display peculiar site-specific features among
all NENs. Their incidence and prevalence have been rising in the past few decades. gNENs …

[HTML][HTML] Peptide receptor radionuclide therapy targeting the somatostatin receptor: basic principles, clinical applications and optimization strategies

N Ahmadi Bidakhvidi, K Goffin, J Dekervel, K Baete… - Cancers, 2021 - mdpi.com
Simple Summary Peptide receptor radionuclide therapy (PRRT) is a systemic treatment
consisting of the administration of a tumor-targeting radiopharmaceutical into the circulation …

A practical proposal on treatment sequencing of metastatic well-differentiated neuroendocrine tumours

M Perrier, JY Scoazec, T Walter - Therapeutic Advances in …, 2023 - journals.sagepub.com
According to the neuroendocrine tumour (NET) characteristics, 3 to 7 different treatment
options are available, corresponding to 6 to 5,040 theoretical different sequences. Even …

Molecular imaging theranostics of neuroendocrine tumors

E Fortunati, N Bonazzi, L Zanoni, S Fanti… - Seminars in Nuclear …, 2023 - Elsevier
Neuroendocrine neoplasms (NEN) are rare and heterogeneous tumors, originating mostly
from the gastro-entero-pancreatic (GEP) tract followed by the lungs. Multidisciplinary …

Clinical features and prognosis of patients with carcinoid syndrome and carcinoid heart disease: a retrospective multicentric study of 276 patients

R Fijalkowski, D Reher, A Rinke, TM Gress… - …, 2022 - karger.com
Introduction: Carcinoid syndrome is the most frequent functional syndrome of
neuroendocrine neoplasia. It is characterized by flushing, diarrhea, wheezing, hypotension …

[HTML][HTML] Peptide Receptor Radionuclide Therapy of Neuroendocrine Tumors: Agonist, Antagonist and Alternatives

G Santo, G Di Santo, I Virgolini - Seminars in Nuclear Medicine, 2024 - Elsevier
Peptide receptor radionuclide therapy (PRRT) today is a well-established treatment strategy
for patients with neuroendocrine tumors (NET). First performed already more than 30 years …

Sequencing of Somatostatin-Receptor–Based Therapies in Neuroendocrine Tumor Patients

JR Strosberg, T Al-Toubah, G El-Haddad… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Most well-differentiated neuroendocrine tumors (NETs) express high levels of somatostatin
receptors, particularly subtypes 2 and 5. Somatostatin analogs (SSAs) bind to somatostatin …

Consideration of quality of life in the treatment decision-making for patients with advanced gastroenteropancreatic neuroendocrine tumors

BG Naraev, J Mailman, TR Halfdanarson… - Expert review of …, 2023 - Taylor & Francis
Introduction Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a complex and
heterogenous family of solid malignancies that originate from neuroendocrine tissue in the …

Therapy Sequencing in Patients With Advanced Neuroendocrine Neoplasms

RP Riechelmann, RG Taboada… - American Society of …, 2023 - ascopubs.org
Neuroendocrine neoplasms (NENs) comprise a beautifully complicated, exciting landscape
of histologies and clinical behaviors. However, the nuanced complexity of low-and high …