Fluorescence image-guided tumour surgery

K Wang, Y Du, Z Zhang, K He, Z Cheng, L Yin… - Nature Reviews …, 2023 - nature.com
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …

Design, Synthesis, and Evaluation of [18F]BIBD-300 as a Positron Emission Tomography Tracer for Poly(ADP-Ribose) Polymerase-1

W Zheng, Y Huang, Y Xie, T Yang, X Cheng… - Molecular …, 2024 - ACS Publications
Compounds 8a–j were designed to adjust the mode of interaction and lipophilicity of FTT by
scaffold hopping and changing the length of the alkoxy groups. Compounds 8a, 8d, 8g, and …

PARP1 promotes EGFR-TKI drug-resistance via PI3K/AKT pathway in non-small-cell lung cancer

X Xu, Y Liu, Q Gong, L Ma, W Wei, L Zhao… - Cancer Chemotherapy …, 2024 - Springer
Purpose Tyrosine kinase inhibitor (TKI) resistance is the main type of drug resistance in lung
cancer patients with epidermal growth factor receptor (EGFR) mutations, but its underlying …