Global brain inflammation in stroke

K Shi, DC Tian, ZG Li, AF Ducruet, MT Lawton… - The Lancet …, 2019 - thelancet.com
Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal
cell death and the release of factors such as damage-associated molecular patterns …

The validity of 18F-GE180 as a TSPO imaging agent

P Zanotti-Fregonara, M Veronese, B Pascual… - European journal of …, 2019 - Springer
Dear Sir, To image the 18-kDa mitochondrial translocator protein (TSPO), a putative
biomarker for inflammation, dozens of PET radioligands have been synthesized over the …

[HTML][HTML] In vivo Imaging of Cannabinoid Type 2 Receptors: Functional and Structural Alterations in Mouse Model of Cerebral Ischemia by PET and MRI

R Ni, A Müller Herde, A Haider, C Keller… - Molecular Imaging and …, 2021 - Springer
Purpose Stroke is one of the most prevalent vascular diseases. Non-invasive molecular
imaging methods have the potential to provide critical insights into the temporal dynamics …

[HTML][HTML] TSPO PET detects acute neuroinflammation but not diffuse chronically activated MHCII microglia in the rat

NU Al-Khishman, Q Qi, AD Roseborough, A Levit… - EJNMMI research, 2020 - Springer
Background Accurate and sensitive imaging biomarkers are required to study the
progression of white matter (WM) inflammation in neurodegenerative diseases …

[HTML][HTML] Longitudinal mouse-PET imaging: a reliable method for estimating binding parameters without a reference region or blood sampling

C Wimberley, DL Nguyen, C Truillet… - European journal of …, 2020 - Springer
Longitudinal mouse PET imaging is becoming increasingly popular due to the large number
of transgenic and disease models available but faces challenges. These challenges are …

Letter to the Editor re: Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in …

P Zanotti-Fregonara, M Veronese, G Rizzo… - Molecular Imaging and …, 2020 - Springer
We read with great interest the recent article of Sridharan et al., in which they investigated
the specific binding of [18F] GE-180 in a population of subjects with multiple sclerosis [1]. By …

Peripheral benzodiazepine receptor/18 kDa translocator protein positron emission tomography imaging in a rat model of acute brain injury

M Nomura, H Toyama, H Suzuki, T Yamada… - Annals of Nuclear …, 2021 - Springer
Objective The activation of microglia in various brain pathologies is accompanied by an
increase in the expression of peripheral benzodiazepine receptor/18 kDa translocator …

[PDF][PDF] Longitudinal mouse-PET imaging: a reliable method for estimating binding parameters without a reference region or blood sampling

ZG Peyronneau, M Tonietto, R Fawzi Boumezbeur… - 2020 - hal.sorbonne-universite.fr
Longitudinal mouse PET imaging is becoming increasingly popular due to the large number
of transgenic and disease models available but faces challenges. These challenges are …