Late imaging with [1-11C] acetate improves detection of tumor fatty acid synthesis with PET

DY Lewis, J Boren, GL Shaw, R Bielik… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Tumors are often characterized by high levels of de novo fatty acid synthesis. The kinetics of
acetate incorporation into tricarboxylic acid cycle intermediates and into lipids suggest that …

Synthesis of [18 F] fluoro-pivalic acid: an improved PET imaging probe for the fatty acid synthesis pathway in tumours

F Pisaneschi, TH Witney, L Iddon, EO Aboagye - MedChemComm, 2013 - pubs.rsc.org
Synthesis of [ 18 F]fluoro-pivalic acid: an improved PET imaging probe for the fatty acid
synthesis pathway in tumours - MedChemComm (RSC Publishing) DOI:10.1039/C3MD00169E …

[PDF][PDF] MedChemComm

F Pisaneschi - researchgate.net
Prostate cancer is the most prevalent of cancers in the male population, accounting for 40
841 incidents in the UK in 2009. 1 In the USA prostate cancer is the second largest cause of …

[HTML][HTML] PET/CT显像剂18F-氟丙酸在肝癌中的生物学评估

赵竞, 张占文, 马慧, 聂大红, 蒋宁一, 刘生… - 国际放射医学核医学 …, 2018 - ijrmnm.com
目的探讨PET/CT 显像剂18 F-氟丙酸(18 F-FPA) 对肝细胞肝癌(HCC) 的显像效果及其摄取机制.
方法(1) 以甲基-2-溴丙酸乙酯为前体合成18 F-FPA;(2) 通过体外细胞摄取实验测定人肝癌SK …