The high incidence rates of prostate cancer (PCa) raise demand for improved therapeutic
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …

Glutamate carboxypeptidase II (GCPII) is a membrane-bound binuclear zinc
metallopeptidase with the highest expression levels found in the nervous and prostatic …

Purpose Since the introduction of positron emission tomography (PET) imaging with 68 Ga-
PSMA-HBED-CC (= 68 Ga-DKFZ-PSMA-11), this method has been regarded as a significant …

Purpose: We have synthesized and evaluated in vivo 2-(3-{1-carboxy-5-[(6-[18F] fluoro-
pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid,[18F] DCFPyL, as a potential …

Gallium-68 is a generator-produced radionuclide for positron emission tomography (PET)
that is being increasingly used for radiolabeling of tumor-targeting peptides. Compounds …

Objective Despite a multitude of detection and treatment advances in the past 2 decades,
prostate cancer remains the second leading cause of deaths due to cancer among men in …

The prostate-specific membrane antigen (PSMA) is a molecular target whose use has
resulted in some of the most productive work toward imaging and treating prostate cancer …

Tumor-associated macrophages constitute a major component of the stroma of solid tumors,
encompassing distinct subpopulations with different characteristics and functions. We aimed …

Prostate-specific membrane antigen (PSMA) continues to be an active biomarker for small-
molecule PSMA-targeted imaging and therapeutic agents for prostate cancer and various …

Prostate cancer continues to represent a major health problem, and yet there is no effective
treatment available for advanced metastatic disease. Thus, there is an urgent need for the …