Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Metal complexes of thiosemicarbazones for imaging and therapy

JR Dilworth, R Hueting - Inorganica Chimica Acta, 2012 - Elsevier
This review gives an account of the coordination chemistry of thiosemicarbazone ligands
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …

Thiosemicarbazone metal complexes: from structure to activity

G Pelosi - The Open Crystallography Journal, 2010 - benthamopen.com
Thiosemicarbazones and their metal complexes are compounds that possess antitumor,
antibacterial, antifungal and antiviral properties. For the foremost majority of cases the …

[HTML][HTML] Imaging of tumor hypoxia with radionuclide-labeled tracers for PET

Y Huang, J Fan, Y Li, S Fu, Y Chen, J Wu - Frontiers in Oncology, 2021 - frontiersin.org
The hypoxic state in a solid tumor refers to the internal hypoxic environment that appears as
the tumor volume increases (the maximum radius exceeds 180-200 microns). This state can …

[HTML][HTML] Nuclear Imaging of Glucose Metabolism: Beyond 18F-FDG

H Feng, X Wang, J Chen, J Cui, T Gao, Y Gao… - Contrast media & …, 2019 - hindawi.com
Glucose homeostasis plays a key role in numerous fundamental aspects of life, and its
dysregulation is associated with many important diseases such as cancer. The atypical …

A brief overview of metal complexes as nuclear imaging agents

DS MacPherson, K Fung, BE Cook… - Dalton …, 2019 - pubs.rsc.org
Metallic radionuclides have been instrumental in the field of nuclear imaging for over half a
century. While recent years have played witness to a dramatic rise in the use of radiometals …

Modification of biodistribution and brain uptake of copper bis (thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups

BM Paterson, C Cullinane, PJ Crouch… - Inorganic …, 2019 - ACS Publications
The synthesis of new bis (thiosemicarbazonato) copper (II) complexes featuring polyamine
substituents via selective transamination reactions is presented. Polyamines of different …

[HTML][HTML] Assessing tumor hypoxia by positron emission tomography with Cu-ATSM

JP Holland, JS Lewis, F Dehdashti - … ,[and] Section of the Society of …, 2009 - ncbi.nlm.nih.gov
For the last several decades, hypoxia has been recognized to be one of the key factors in
tumor aggression and an important impediment to local and distant control of malignant …

Preparation, characterization of 2-deoxy-D-glucose functionalized dimercaptosuccinic acid-coated maghemite nanoparticles for targeting tumor cells

F Xiong, Z Zhu, C Xiong, X Hua, X Shan, Y Zhang… - Pharmaceutical …, 2012 - Springer
Purpose To report a modified preparation and to systematically study the structure, magnetic
and other properties of γ-Fe 2 O 3-DMSA-DG NPs (2-deoxy-D-glucose (2-DG) conjugated …

Fluorescent gallium and indium bis (thiosemicarbazonates) and their radiolabelled analogues: Synthesis, structures and cellular confocal fluorescence imaging …

RL Arrowsmith, PA Waghorn, MW Jones… - Dalton …, 2011 - pubs.rsc.org
New fluorescent and biocompatible aromatic Ga (III)-and In (III)-bis (thiosemicarbazonato)
complexes for dual mode optical and PET or SPECT molecular imaging have been …