Ionizing radiation and the immune response

RE Anderson, NL Warner - Advances in immunology, 1976 - Elsevier
Publisher Summary This chapter illustrates several ways in which radiation may be
employed to dissect several individual cellular components of the immune response. The …

PET tracers based on Zirconium-89

Y Zhang, H Hong, W Cai - Current radiopharmaceuticals, 2011 - ingentaconnect.com
Positron emission tomography (PET) imaging with radiolabeled monoclonal antibodies has
always been a dynamic area in molecular imaging. With decay half-life (3.3 d) well matched …

Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges

TK Nayak, MW Brechbiel - Bioconjugate chemistry, 2009 - ACS Publications
Radioimmunoimaging and therapy has been an area of interest for several decades. Steady
progress has been made toward clinical translation of radiolabeled monoclonal antibodies …

The old CEACAMs find their new role in tumor immunotherapy

ZW Han, ZW Lyv, B Cui, YY Wang, JT Cheng… - Investigational New …, 2020 - Springer
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) contain 12 family
members (CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6, CEACAM7 …

[HTML][HTML] Positron Emission Tomography Imaging of CD105 Expression with a 64Cu-Labeled Monoclonal Antibody: NOTA Is Superior to DOTA

Y Zhang, H Hong, JW Engle, J Bean, Y Yang… - PloS one, 2011 - journals.plos.org
Optimizing the in vivo stability of positron emission tomography (PET) tracers is of critical
importance to cancer diagnosis. In the case of 64Cu-labeled monoclonal antibodies (mAb) …

[PDF][PDF] Technetium-99m labeling of antibodies to cardiac myosin Fab and to human fibrinogen

BA Khaw, HW Strauss, A Carvalho… - Journal of Nuclear …, 1982 - Soc Nuclear Med
We havedevelopeda methodof labelingbiologicallyactivelabilemacromole cules, suchas
humanfibrinogen (HF) and anticardiac-myosinFab (AM-Fab), with Tc-99m at neutralpH. This …

Novel radiolabeled antibody conjugates

DM Goldenberg, RM Sharkey - Oncogene, 2007 - nature.com
This article reviews the development of radioimmunoconjugates as a new class of cancer
therapeutics. Numerous conjugates involving different antigen targets, antibody forms …

Recombinant bispecific monoclonal antibodies prepared by the dock-and-lock strategy for pretargeted radioimmunotherapy

RM Sharkey, EA Rossi, WJ McBride, CH Chang… - Seminars in nuclear …, 2010 - Elsevier
The selective delivery of therapeutic radionuclides is a promising approach for treating
cancer. Antibody-targeted radionuclides are of particular interest, with 2 products approved …

Fibrinolysis and cancer

HC Kwaan, HN Keer - Seminars in thrombosis and hemostasis, 1990 - thieme-connect.com
Although Trousseau1 was the earliest observer who noted the association between cancer
and thrombosis, it was Billroth2 who first described the presence of tumor cells within a …

[HTML][HTML] Feasibility of PET/CT system performance harmonisation for quantitative multicentre 89Zr studies

A Kaalep, M Huisman, T Sera, D Vugts, R Boellaard… - EJNMMI physics, 2018 - Springer
Purpose The aim of this study was to investigate the variability in quantitative performance
and feasibility of quantitative harmonisation in 89 Zr PET/CT imaging. Methods Eight EANM …