The low efficiency of treatment strategies is one of the main obstacles to developing cancer
inhibitors. Up to now, various classes of therapeutics have been developed to inhibit cancer …

Recent advances in molecularly targeted modular designs for in vivo imaging applications
has thrusted open possibilities of investigating deep molecular interactions non-invasively …

Purpose Clinical studies on the use of ascorbic acid (AA) have become a hot spot in cancer
research. There remains an unmet need to assess AA utilization in normal tissues and …

Background The lack of noninvasive methods for assessment of dysregulated inflammation
as a major driver of fibrosis (ie, inflammation-fibrosis axis) has been a major challenge to …

The 68Ga-Collagen Binding Probe# 8, 68Ga-CBP8, is a peptide-based, type I collagen–
targeted probe developed for imaging of tissue fibrosis. The aim of this study was to …

In this work, we synthesized two new benzo-18-azacrown-6 ethers bearing picolinate and
pyridine pendant arms and studied the copper complexes of these ligands, as well as those …

Fibrosis is a progressive pathological process participating in the progression of many
diseases and can ultimately result in organ malfunction and failure. Around 45% of deaths in …

Positron emission tomography (PET) is an imaging modality used for the noninvasive
assessment of tumor staging and response to therapy. PET with 18F labeled …

Recent advances in molecularly targeted modular designs for in vivo imaging applications
has thrusted open possibilities of investigating deep molecular interactions non-invasively …

Targeted radiopharmaceutical therapy (TRT) involving systemic administration of a tumor-
selective agent labeled with a radionuclide has demonstrated considerable promise for …