[HTML][HTML] Fluorinated carbohydrates for 18 F-positron emission tomography (PET)

E Campbell, C Jordan, R Gilmour - Chemical Society Reviews, 2023 - pubs.rsc.org
Carbohydrate diversity is foundational in the molecular literacy that regulates cellular
function and communication. Consequently, delineating and leveraging this structure …

Measuring pathology in patients with multiple sclerosis using positron emission tomography

MR Brier, F Taha - Current neurology and neuroscience reports, 2023 - Springer
Abstract Purpose of Review Multiple sclerosis is characterized by a diverse and complex
pathology. Clinical relapses, the hallmark of the disease, are accompanied by focal white …

[HTML][HTML] Multimodal molecular imaging reveals tissue-based T cell activation and viral RNA persistence for up to 2 years following COVID-19

MJ Peluso, D Ryder, R Flavell, Y Wang, J Levi… - medRxiv, 2023 - ncbi.nlm.nih.gov
The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms
(Long COVID) following SARS-CoV-2 infection are incompletely understood. There is …

[HTML][HTML] Biodistribution of a Mitochondrial Metabolic Tracer, [18F]F-AraG, in Healthy Volunteers

J Levi, H Duan, S Yaghoubi, J Packiasamy… - Molecular …, 2022 - hindawi.com
Purpose.[18 F] F-AraG is a radiolabeled nucleoside analog that shows relative specificity for
activated T cells. The aim of this study was to investigate the biodistribution of [18 F] F-AraG …

[HTML][HTML] Radionuclide imaging of cytotoxic immune cell responses to anti-cancer immunotherapy

L Lauwerys, E Smits, T Van den Wyngaert, F Elvas - Biomedicines, 2022 - mdpi.com
Cancer immunotherapy is an evolving and promising cancer treatment that takes advantage
of the body's immune system to yield effective tumor elimination. Importantly, immunotherapy …

[HTML][HTML] The other immuno-PET: Metabolic tracers in evaluation of immune responses to immune checkpoint inhibitor therapy for solid tumors

J Levi, H Song - Frontiers in Immunology, 2023 - frontiersin.org
Unique patterns of response to immune checkpoint inhibitor therapy, discernable in the
earliest clinical trials, demanded a reconsideration of the standard methods of radiological …

HIV compartmentalization in the CNS and its impact in treatment outcomes and cure strategies

P Chan, S Spudich - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review This review focuses on the cerebrospinal fluid (CSF) findings in
connection to the central nervous system (CNS) reservoir in treatment-naïve and virally …

The Promise of Molecular Imaging: Focus on Central Nervous System Infections

S Shah, ML Turner, X Chen, BM Ances… - The Journal of …, 2023 - academic.oup.com
Central nervous system (CNS) infections can lead to high mortality and severe morbidity.
Diagnosis, monitoring, and assessing response to therapy of CNS infections is particularly …

[HTML][HTML] Visual evoked potentials waveform analysis to measure intracortical damage in a preclinical model of multiple sclerosis

S Marenna, E Rossi, SC Huang, V Castoldi… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction: Visual evoked potentials (VEPs) are a non-invasive technique routinely used in
clinical and preclinical practice. Discussion about the inclusion of VEPs in McDonald criteria …

Brain inflammation in experimental autoimmune encephalomyelitis induced in Dark Agouti rats with spinal cord homogenate

G Stegnjaić, B Jevtić, M Lazarević, Đ Ignjatović… - Immunology …, 2024 - Elsevier
We have recently characterized experimental autoimmune encephalomyelitis (EAE) induced
in DA rats with spinal cord homogenate without complete Freund's adjuvant (CFA). The main …