[HTML][HTML] Decreased synaptic vesicle glycoprotein 2A binding in a rodent model of familial Alzheimer's disease detected by [18F]SDM-16

C Zheng, T Toyonaga, B Chen, LS Nicholson… - Frontiers in …, 2023 - frontiersin.org
Introduction Synapse loss is one of the hallmarks of Alzheimer's disease (AD) and is
associated with cognitive decline. In this study, we tested [18F] SDM-16, a novel …

Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density

Y Yang, C Zheng, B Chen, NC Hernandez, PL Faust… - The Cerebellum, 2023 - Springer
Objective Despite being one of the most prevalent neurological diseases, the
pathophysiology of essential tremor (ET) is not fully understood. Neuropathological studies …

Decreased synaptic vesicle glycoprotein A binding in a rodent model of familial Alzheimer's disease detected by [F] SDM

C Zheng, T Toyonaga, B Chen… - Cancer and Central …, 2023 - books.google.com
Methods: Based on previous preclinical PET imaging studies using [C] UCB-J and [F]
SynVesT-in the same strain animals, we used the simplified reference tissue model (SRTM) …