FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease
Y Mori, K Dendl, J Cardinale, C Kratochwil, FL Giesel… - Radiology, 2023 - pubs.rsna.org
Gallium 68 (68Ga)–labeled fibroblast activation protein (FAP) inhibitor (FAPI) PET is based
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
[HTML][HTML] Fibroblast activation protein-based theranostics in cancer research: a state-of-the-art review
In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …
shown promising results in the diagnosis of cancer and several other diseases, making them …
Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Evaluation of Advanced Lung Cancer
L Wang, G Tang, K Hu, X Liu, W Zhou, H Li, S Huang… - Radiology, 2022 - pubs.rsna.org
Background Gallium 68 (68Ga)–labeled fibroblast-activation protein inhibitor (FAPI) has
recently been introduced as a promising tumor imaging agent. Purpose To compare 68Ga …
recently been introduced as a promising tumor imaging agent. Purpose To compare 68Ga …
State-of-the-art of FAPI-PET imaging: a systematic review and meta-analysis
Introduction Fibroblast activation protein-α (FAPα) is overexpressed on cancer-associated
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …
[HTML][HTML] FAP and FAPI-PET/CT in malignant and non-malignant diseases: a perfect symbiosis?
K Dendl, SA Koerber, C Kratochwil, J Cardinale… - Cancers, 2021 - mdpi.com
Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …
results in terms of a high uptake in concordance with low background noise in several …
Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
Simultaneous FAPI PET/MRI targeting the fibroblast-activation protein for breast cancer
P Backhaus, MC Burg, W Roll, F Büther, HJ Breyholz… - Radiology, 2022 - pubs.rsna.org
Background Integrated PET/MRI is a promising modality for breast assessment. The most
frequently used tracer, fluorine 18 (18F) fluorodeoxyglucose (FDG), is applied for whole …
frequently used tracer, fluorine 18 (18F) fluorodeoxyglucose (FDG), is applied for whole …
Comparison of [68 Ga]Ga-DOTA-FAPI-04 PET/CT and [18F]FDG PET/CT in colorectal cancer
H Kömek, C Can, İ Kaplan, C Gündoğan… - European Journal of …, 2022 - Springer
Aim In this study, we aimed to evaluate the diagnostic sensitivity of [68 Ga] Ga-DOTA-FAPI-
04 PET/CT in the evaluation of primary or recurrent tumor, and nodal, peritoneal, and distant …
04 PET/CT in the evaluation of primary or recurrent tumor, and nodal, peritoneal, and distant …
68Ga-DOTA-FAPI-04 PET/MR in the evaluation of gastric carcinomas: comparison with 18F-FDG PET/CT
C Qin, F Shao, Y Gai, Q Liu, W Ruan, F Liu… - Journal of Nuclear …, 2022 - Soc Nuclear Med
We sought to evaluate the performance of 68Ga-DOTA-FAPI-04 (68 Ga-FAPI) PET/MR for
the diagnosis of primary tumor and metastatic lesions in patients with gastric carcinomas …
the diagnosis of primary tumor and metastatic lesions in patients with gastric carcinomas …
[HTML][HTML] Head-to-head comparison of [68Ga]Ga-FAPI-04 and [18F]-FDG PET/CT in evaluating the extent of disease in gastric adenocarcinoma
J Kuten, C Levine, O Shamni, S Pelles, I Wolf… - European Journal of …, 2022 - Springer
Abstract Background [18 F]-Fluorodeoxyglucose (FDG) positron emission tomography–
computed tomography (PET/CT) may sometimes be suboptimal for imaging gastric …
computed tomography (PET/CT) may sometimes be suboptimal for imaging gastric …