Imaging-guided targeted radionuclide tumor therapy: From concept to clinical translation
J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …
[HTML][HTML] Personalized dosimetry in targeted radiation therapy: a look to methods, tools and critical aspects
R Danieli, A Milano, S Gallo, I Veronese… - Journal of Personalized …, 2022 - mdpi.com
Targeted radiation therapy (TRT) is a strategy increasingly adopted for the treatment of
different types of cancer. The urge for optimization, as stated by the European Council …
different types of cancer. The urge for optimization, as stated by the European Council …
[PDF][PDF] Normal-tissue tolerance to radiopharmaceutical therapies, the knowns and the unknowns
Radiopharmaceutical therapies are gaining increasing prominence as they improve survival
in patients with common diseases such as metastatic prostate cancer (1, 2). However …
in patients with common diseases such as metastatic prostate cancer (1, 2). However …
18F-FDOPA PET for the noninvasive prediction of glioma molecular parameters: a radiomics study
The assessment of gliomas by 18F-FDOPA PET imaging as an adjunct to MRI showed high
performance by combining static and dynamic features to noninvasively predict the isocitrate …
performance by combining static and dynamic features to noninvasively predict the isocitrate …
[HTML][HTML] The relationship between tumour dosimetry, response, and overall survival in patients with unresectable Neuroendocrine Neoplasms (NEN) treated with 177 …
Abstract Peptide Receptor Radionuclide Therapy (PRRT) delivers targeted radiation to
Somatostatin Receptor (SSR) expressing Neuroendocrine Neoplasms (NEN). We sought to …
Somatostatin Receptor (SSR) expressing Neuroendocrine Neoplasms (NEN). We sought to …
[HTML][HTML] Understanding the Radiobiological Mechanisms Induced by 177Lu-DOTATATE in Comparison to External Beam Radiation Therapy
W Delbart, J Karabet, G Marin, S Penninckx… - International journal of …, 2022 - mdpi.com
Radionuclide Therapy (RNT) with 177Lu-DOTATATE targeting somatostatin receptors
(SSTRs) in neuroendocrine tumours (NET) has been successfully used in routine clinical …
(SSTRs) in neuroendocrine tumours (NET) has been successfully used in routine clinical …
[HTML][HTML] Toxicity Assessment of [177Lu]Lu−iFAP/iPSMA Nanoparticles Prepared under GMP-Compliant Radiopharmaceutical Processes
T Hernández-Jiménez, P Cruz-Nova, A Ancira-Cortez… - Nanomaterials, 2022 - mdpi.com
The fibroblast activation protein (FAP) is heavily expressed in fibroblasts associated with the
tumor microenvironment, while the prostate-specific membrane antigen (PSMA) is …
tumor microenvironment, while the prostate-specific membrane antigen (PSMA) is …
[HTML][HTML] Developments in combining targeted radionuclide therapies and immunotherapies for cancer treatment
CP Kerr, JJ Grudzinski, TP Nguyen, R Hernandez… - Pharmaceutics, 2022 - mdpi.com
Targeted radionuclide therapy (TRT) and immunotherapy are rapidly growing classes of
cancer treatments. Basic, translational, and clinical research are now investigating …
cancer treatments. Basic, translational, and clinical research are now investigating …
A radiomic‐ and dosiomic‐based machine learning regression model for pretreatment planning in 177Lu‐DOTATATE therapy
D Plachouris, V Eleftheriadis, T Nanos… - Medical …, 2023 - Wiley Online Library
Background Standardized patient‐specific pretreatment dosimetry planning is mandatory in
the modern era of nuclear molecular radiotherapy, which may eventually lead to …
the modern era of nuclear molecular radiotherapy, which may eventually lead to …
SPECT at the speed of PET: a feasibility study of CZT-based whole-body SPECT/CT in the post 177Lu-DOTATATE and 177Lu-PSMA617 setting
Purpose To evaluate the feasibility of using the StarGuide (General Electric Healthcare,
Haifa, Israel), a new generation multi-detector cadmium-zinc-telluride (CZT)-based …
Haifa, Israel), a new generation multi-detector cadmium-zinc-telluride (CZT)-based …