[HTML][HTML] Astatine-211 based radionuclide therapy: Current clinical trial landscape
P Albertsson, T Bäck, K Bergmark, A Hallqvist… - Frontiers in …, 2023 - frontiersin.org
Astatine-211 (211At) has physical properties that make it one of the top candidates for use
as a radiation source for alpha particle-based radionuclide therapy, also referred as targeted …
as a radiation source for alpha particle-based radionuclide therapy, also referred as targeted …
[HTML][HTML] Clinical advances and perspectives in targeted radionuclide therapy
N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …
Pretargeting: a path forward for radioimmunotherapy
Pretargeted radioimmunodiagnosis and radioimmunotherapy aim to efficiently combine
antitumor antibodies and medicinal radioisotopes for high-contrast imaging and high …
antitumor antibodies and medicinal radioisotopes for high-contrast imaging and high …
Synthetic host-guest pairs as novel bioorthogonal tools for pre-targeting
YL Ma, S Yan, XJ Xu, H Cao, R Wang - Chinese Chemical Letters, 2024 - Elsevier
Due to its simplicity, high efficiency, and chemo-selectivity, bioorthogonal chemistry has
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
[HTML][HTML] Radiometals in Imaging and Therapy: Highlighting Two Decades of Research
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …
[HTML][HTML] Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy
JA Navarro-Becerra, MA Borden - Pharmaceutics, 2023 - mdpi.com
Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
Investigation of Copper-64-Based Host–Guest Chemistry Pretargeted Positron Emission Tomography
VIJ Jallinoja, BD Carney, K Bhatt… - Molecular …, 2022 - ACS Publications
Pretargeting is a technique that uses macromolecules as targeting agents for nuclear
imaging and therapy with the goal of reducing the radiation toxicity to healthy tissues often …
imaging and therapy with the goal of reducing the radiation toxicity to healthy tissues often …
[HTML][HTML] Radiotheranostic agents in hematological malignancies
J Caers, E Duray, L Vrancken, G Marcion… - Frontiers in …, 2022 - frontiersin.org
Radioimmunotherapy (RIT) is a cancer treatment that combines radiation therapy with tumor-
directed monoclonal antibodies (Abs). Although RIT had been introduced for the treatment of …
directed monoclonal antibodies (Abs). Although RIT had been introduced for the treatment of …
[HTML][HTML] Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211
C Timperanza, H Jensen, T Bäck, S Lindegren… - Pharmaceuticals, 2023 - mdpi.com
To enhance targeting efficacy in the radioimmunotherapy of disseminated cancer, several
pretargeting strategies have been developed. In pretargeted radioimmunotherapy, the tumor …
pretargeting strategies have been developed. In pretargeted radioimmunotherapy, the tumor …
Pretargeting with Cucurbituril–Adamantane Host–Guest Pair in Xenograft Models
VIJ Jallinoja, CH Abbriano, K Bhatt, A Kaur… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The goal of reducing the total-body radiation dose of macromolecule-based nuclear
medicine with a 2-step pretargeting strategy has been achieved with several pretargeting …
medicine with a 2-step pretargeting strategy has been achieved with several pretargeting …