[HTML][HTML] Radiolabeled PSMA inhibitors

OC Neels, K Kopka, C Liolios, A Afshar-Oromieh - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer remains one of the leading causes of cancer death in men
worldwide. Despite the recent success in the development and clinical application of …

[HTML][HTML] Molecular imaging in primary staging of prostate cancer patients: current aspects and future trends

R Manafi-Farid, S Ranjbar, Z Jamshidi Araghi, J Pilz… - Cancers, 2021 - mdpi.com
Simple Summary Accurate primary staging for determining the extent of prostate cancer is
crucial for planning treatment in high-risk patients for distant metastases. Recurrence is still …

[HTML][HTML] The role of [99mTc]Tc-HFAPi SPECT/CT in patients with malignancies of digestive system: first clinical experience

X Jia, X Li, B Jia, Y Yang, Y Wang, Y Liu, T Ji… - European Journal of …, 2023 - Springer
Abstract Background Recently, PET/CT imaging with radiolabelled FAP inhibitors (FAPIs)
has been widely evaluated in diverse diseases. However, rare report has been published …

Delayed imaging improves lesion detectability in [99mTc] Tc-PSMA-I&S SPECT/CT in recurrent prostate cancer

C Berliner, L Steinhelfer, M Chantadisai… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Our objective was to compare the ability to detect histopathologically confirmed lymph node
metastases by early and delayed [99mTc] Tc-PSMA-I&S SPECT/CT in early biochemically …

PSMA-GCK01: a generator-based 99mTc/188Re theranostic ligand for the prostate-specific membrane antigen

J Cardinale, FL Giesel, C Wensky… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) theranostics have been introduced with 68Ga
and 177Lu, the most used radionuclides. However, 188Re is a well-known generator-based …

[HTML][HTML] Preclinical Evaluation of a Novel High-Affinity Radioligand [99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA)

E Bezverkhniaia, P Kanellopoulos… - International Journal of …, 2023 - mdpi.com
Radionuclide imaging using radiolabeled inhibitors of prostate-specific membrane antigen
(PSMA) can be used for the staging of prostate cancer. Previously, we optimized the Glu …

[HTML][HTML] Synthesis and preclinical evaluation of novel 99mTc-labeled PSMA ligands for radioguided surgery of prostate cancer

JP Kunert, M Müller, T Günther, L Stopper… - EJNMMI research, 2023 - Springer
Background Radioguided surgery (RGS) has recently emerged as a valuable new tool in the
management of recurrent prostate cancer (PCa). After preoperative injection of a 99mTc …

[HTML][HTML] Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model

P Dell'Oglio, DM van Willigen, MN van Oosterom… - EJNMMI research, 2022 - Springer
Background With the rise of prostate-specific membrane antigen (PSMA) radioguided
surgery, which is performed using a microdosing regime, demand for visual target …

Diagnostic value of [99mTc]Tc-PSMA-I&S-SPECT/CT for the primary staging and restaging of prostate cancer

I Farkas, G Sipka, A Bakos, A Maráz… - Therapeutic …, 2024 - journals.sagepub.com
Background: A large number of studies have proved that prostate-specific membrane
antigen-positron emission tomography/computer tomography (PSMA-PET/CT) provides …

Dosimetry estimation and preliminary clinical application of [99mTc]Tc-HYNIC-PSMA-XL-2 in prostate cancer

H Yang, Z Gao, X Xu, C Liu, S Hu, J Zhang… - Annals of Nuclear …, 2023 - Springer
Objective Molecular imaging of prostate-specific membrane antigen (PSMA) inhibitors has
become a favorite for prostate cancer (PCa). This study aimed to estimate the dosimetry and …