Quantitative PET-based biomarkers in lymphoma: getting ready for primetime

JP Alderuccio, RA Kuker, F Yang… - Nature Reviews Clinical …, 2023 - nature.com
The use of functional quantitative biomarkers extracted from routine PET–CT scans to
characterize clinical responses in patients with lymphoma is gaining increased attention …

[HTML][HTML] Pan-immune-inflammation value independently predicts disease recurrence in patients with Merkel cell carcinoma

T Gambichler, S Said, N Abu Rached… - Journal of Cancer …, 2022 - Springer
Purpose We aimed to determine whether the pan-immune-inflammation value (PIV) of
patients with Merkel cell carcinoma (MCC) at primary diagnosis differs from controls and …

Prognostic value of presalvage metabolic tumor volume in patients with relapsed/refractory diffuse large B-cell lymphoma

JP Alderuccio, RA Kuker, P Barreto-Coelho… - Leukemia & …, 2022 - Taylor & Francis
Identification of new prognostic factors in relapsed/refractory (rel/ref) diffuse large B-cell
lymphoma (DLBCL) is essential for developing risk-adapted approaches. We retrospectively …

PET/CT Biomarkers Enable Risk Stratification of Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma Enrolled in the LOTIS-2 Clinical Trial

JP Alderuccio, IM Reis, M Hamadani… - Clinical cancer …, 2024 - AACR
Purpose: Significant progress has occurred in developing quantitative PET/CT biomarkers in
diffuse large B-cell lymphoma (DLBCL). Total metabolic tumor volume (MTV) is the most …

Tumor glycolytic heterogeneity improves detection of regional nodal metastasis in patients with lung adenocarcinoma

KH Lue, SC Chu, LY Wang, YC Chen, MH Li… - Annals of Nuclear …, 2022 - Springer
Objective The diagnostic performance of 18 F-FDG PET for detecting regional lymph node
metastasis in resectable lung cancer is variable, and its sensitivity for adenocarcinoma is …

A comparison of 18F-FDG PET-based radiomics and deep learning in predicting regional lymph node metastasis in patients with resectable lung adenocarcinoma: a …

KH Lue, YH Chen, SC Chu, BS Chang… - Nuclear Medicine …, 2023 - journals.lww.com
Objective The performance of 18 F-FDG PET-based radiomics and deep learning in
detecting pathological regional nodal metastasis (pN+) in resectable lung adenocarcinoma …

[HTML][HTML] Systemic inflammation index and tumor glycolytic heterogeneity help risk stratify patients with advanced epidermal growth factor receptor-mutated lung …

KH Lue, CH Huang, TC Hsieh, SH Liu, YF Wu… - Cancers, 2022 - mdpi.com
Simple Summary Patients with advanced epidermal growth factor receptor (EGFR)-mutated
lung adenocarcinoma have been known to respond to first-line tyrosine kinase inhibitor (TKI) …

Glucose metabolic heterogeneity correlates with pathological features and improves survival stratification of resectable lung adenocarcinoma

YH Chen, YC Chen, KH Lue, SC Chu… - Annals of Nuclear …, 2023 - Springer
Objective We investigated whether glycolytic heterogeneity correlated with histopathology,
and further stratified the survival outcomes pertaining to resectable lung adenocarcinoma …

[HTML][HTML] Highly sensitive detection of CYFRA21-1 with a SERS sensing platform based on the MBs enrichment strategy and antibody-DNA-mediated CHA …

X Bao, S Wang, X Liu, G Li - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Laryngeal carcinoma (LC) is the second most common malignant tumor of the head and
neck. Due to its insidious nature, most patients have developed to the middle and late …

Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein …

JF Marcelletti, BI Sikic - Cancer Chemotherapy and Pharmacology, 2024 - Springer
Purpose To evaluate the safety, tolerability, pharmacodynamics (PD), and potential efficacy
of zosuquidar (Zos) in combination with daunorubicin and cytarabine in elderly patients with …