Molecular imaging of chemokine-like receptor 1 (CMKLR1) in experimental acute lung injury

PZ Mannes, CE Barnes, J Biermann… - Proceedings of the …, 2023 - National Acad Sciences
The lack of techniques for noninvasive imaging of inflammation has challenged precision
medicine management of acute respiratory distress syndrome (ARDS). Here, we determined …

[HTML][HTML] Molecular Imaging of Fibrosis in Benign Diseases: An Overview of the State of the Art

Y Zhang, W Huang, H Jiao, L Song, L Kang - Pharmaceuticals, 2024 - mdpi.com
Fibrosis is a progressive pathological process participating in the progression of many
diseases and can ultimately result in organ malfunction and failure. Around 45% of deaths in …

[HTML][HTML] 2-deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography to Monitor Lung Inflammation and Therapeutic Response to Dexamethasone in a Murine …

PZ Mannes, CE Barnes, JD Latoche, KE Day… - Molecular Imaging and …, 2023 - Springer
Purpose To image inflammation and monitor therapeutic response to anti-inflammatory
intervention using 2-deoxy-2-[18F] fluoro-D-glucose ([18F] FDG) positron emission …

[HTML][HTML] Targeted imaging of very late antigen-4 for noninvasive assessment of lung inflammation-fibrosis axis

Q Zhu, CE Barnes, PZ Mannes, JD Latoche, KE Day… - EJNMMI research, 2023 - Springer
Background The lack of noninvasive methods for assessment of dysregulated inflammation
as a major driver of fibrosis (ie, inflammation-fibrosis axis) has been a major challenge to …

[HTML][HTML] Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury

D Xu, F Yang, J Chen, T Zhu, F Wang, Y Xiao… - … Pharmaceutica Sinica B, 2023 - Elsevier
Acute lung injury (ALI), as a common clinical emergency, is pulmonary edema and diffuse
lung infiltration caused by inflammation. The lack of non-invasive alert strategy, resulting in …

Adhesion molecule–targeted magnetic particle imaging nanoprobe for visualization of inflammation in acute lung injury

P Gao, Y Liu, X Wang, X Feng, H Liu, S Liu… - European Journal of …, 2023 - Springer
Purpose Uncontrolled intra-alveolar inflammation is a central pathogenic feature, and its
severity translates into a valid prognostic indicator of acute lung injury (ALI). Unfortunately …

Visualizing γδ T cells by very late antigen-4-targeted positron emission tomography

Y Long, X Lv, X Song, F Shao, H Ji, Y Zhang… - European journal of …, 2022 - Springer
Purpose γδ T cell–based immunotherapy has been rolled out as a promising treatment
strategy for malignant tumors due to their potent anti-tumor cytotoxicity, ease of expansion …

[PDF][PDF] Molecular imaging of chemokine-like receptor 1 (CMKLR1) for non-invasive monitoring of monocyte-derived macrophages in experimental lung injury and …

P Mannes - 2023 - d-scholarship.pitt.edu
There is a lack of techniques for noninvasive imaging of pulmonary inflammation associated
with acute lung injury and pulmonary fibrosis. Here we determined the potential of positron …

Development of a PET-Based Theranostic for Drug-Resistant BRAFV600EMelanoma

MC Bellavia - 2023 - search.proquest.com
Targeted radiopharmaceutical therapy (TRT) involving systemic administration of a tumor-
selective agent labeled with a radionuclide has demonstrated considerable promise for …

Magnetic Particle Imaging for in Vivo Imaging of Acute Lung Injury

P Gao, X Feng, H Hui, J Tian… - International Journal on …, 2023 - journal.iwmpi.org
Acute lung injury leads to impaired of lung function, has a high morbidity and mortality, and
the disease burden is large for the patient. Because the lung is a spongy organ with many …