Purpose Assess the individual and combined diagnostic value of amyloid-PET and tau-PET
in a memory clinic population. Methods Clinical reports of 136 patients were randomly …

Featured Application A thorough review of the quantitative methods for the detection of
Alzheimer's from neuroimaging studies acquired with positron emission tomography, with a …

The recent development of several tau positron emission tomography (PET) tracers
represents a major milestone for the Alzheimer's disease (AD) field. These tau PET tracers …

Alzheimer's disease is defined by the presence of β-amyloid plaques and neurofibrillary tau
tangles potentially preceding clinical symptoms by many years. Previously only detectable …

Introduction Positron emission tomography (PET) imaging targeting neurofibrillary tau
tangles is increasingly used in the study of Alzheimer's disease (AD), but its utility may be …

INTRODUCTION Alzheimer's disease (AD) is characterized by the presence of both amyloid
and tau pathology. In vivo diagnosis can be made with amyloid and tau positron emission …

Tau deposition plays a critical role over cognition and neurodegeneration in Alzheimer's
disease (AD). Recent generation tracers have high target to background ratios giving a wide …

The improvement of existing techniques and the development of new molecular imaging
methods are an exciting and rapidly developing field in clinical care and research of …

Background: Recent advances occurred in the field of Alzheimer's disease (AD) biomarkers
and the introduction of a research framework grounded on a biomarker-based definition of …

Background Idiopathic normal pressure hydrocephalus (iNPH) is primarily characterized by
cognitive impairment and gait disturbance. Our objective was to evaluate the clinical …