Highlights•Nanobodies are ideal candidates for molecular imaging.•A key variable
determining the in vivo performance of a nanobody-derived molecular imaging tracer is the …

The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Single-domain antibody fragments (sdAbs) are attractive for targeted α-particle therapy,
particularly with 211At, because of their rapid accumulation in tumor and clearance from …

Single-domain antibody (sdAb) is among the most promising vectors for developing
molecular imaging tracers. Several sdAb tracers targeting human epidermal growth factor …

Purpose The high expression of the transmembrane glycoprotein trophoblast cell-surface
antigen 2 (Trop2) was strongly associated with the progression of solid tumors, including …

Purpose Human epidermal growth factor receptor 2 (HER2)-positive breast cancer cases
are among the most aggressive breast tumor subtypes. Accurately assessing HER2 …

Human epidermal growth factor receptor 2 (HER2) has emerged as an important molecular
target for tumor diagnosis and therapy. The H6F peptide (YLFFVFER) selectively binds to …

Anchoring an imidazole‐di‐tert‐butyl‐arylsilane possessing an azido group to a polystyrene
resin provided a heterogeneous precursor that was radiolabeled easily using aqueous [18F] …

Pretargeted PET imaging using bioorthogonal chemistry is a leading strategy for the tracking
of long-circulating agents such as antibodies and nanoparticle-drug delivery systems with …

First and foremost, I want to thank my supervisor, Dr Rafael TM de Rosales for your support
and guidance over the last 5 years. You have not only been my thesis supervisor but also …