Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

[HTML][HTML] Long axial field of view PET scanners: a road map to implementation and new possibilities

RHJA Slart, C Tsoumpas, AWJM Glaudemans… - European journal of …, 2021 - Springer
In this contribution, several opportunities and challenges for long axial field of view (LAFOV)
PET are described. It is an anthology in which the main issues have been highlighted. A …

[HTML][HTML] Imaging inflammation with positron emission tomography

J Iking, M Staniszewska, L Kessler, JM Klose… - Biomedicines, 2021 - mdpi.com
The impact of inflammation on the outcome of many medical conditions such as
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …

[HTML][HTML] Molecular imaging of the brain–heart axis provides insights into cardiac dysfunction after cerebral ischemia

N Hermanns, V Wroblewski, P Bascuñana… - Basic Research in …, 2022 - Springer
Ischemic stroke imparts elevated risk of heart failure though the underlying mechanisms
remain poorly described. We aimed to characterize the influence of cerebral ischemic injury …

Targeted PET imaging of chemokine receptor 2–positive monocytes and macrophages in the injured heart

GS Heo, G Bajpai, W Li, HP Luehmann… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Proinflammatory macrophages are important mediators of inflammation after myocardial
infarction and of allograft injury after heart transplantation. The aim of this study was to …

Spinal cord astrocytes regulate myocardial ischemia–reperfusion injury

C Wu, R Liu, Z Luo, M Sun, M Qile, S Xu, S Jin… - Basic research in …, 2022 - Springer
Astrocytes play a key role in the response to injury and noxious stimuli, but its role in
myocardial ischemia–reperfusion (I/R) injury remains largely unknown. Here we determined …

[HTML][HTML] Cognitive dysfunction after heart disease: a manifestation of the heart-brain axis

C Xu, X Tao, X Ma, R Zhao, Z Cao - Oxidative Medicine and Cellular …, 2021 - hindawi.com
The functions of the brain and heart, which are the two main supporting organs of human
life, are closely linked. Numerous studies have expounded the mechanisms of the brain …

[HTML][HTML] Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro) inflammation and behavior after myocardial …

L Gouweleeuw, H Wajant, O Maier, ULM Eisel… - Brain, Behavior, and …, 2021 - Elsevier
Background Myocardial infarction (MI) coinciding with depression worsens prognosis.
Although Tumor Necrosis Factor alpha (TNF) is recognized to play a role in both conditions …

Multimodality molecular imaging: Gaining insights into the mechanisms linking chronic stress to cardiovascular disease

MT Osborne, S Abohashem, H Zureigat… - Journal of Nuclear …, 2021 - Elsevier
Positron emission tomography (PET) imaging can yield unique mechanistic insights into the
pathophysiology of atherosclerosis. 18 F-fluorodeoxyglucose (18 F-FDG), a radiolabeled …

Assessment of cerebral glucose metabolism in patients with heart failure by 18F-FDG PET/CT imaging

M Yun, B Nie, W Wen, Z Zhu, H Liu, S Nie… - Journal of Nuclear …, 2022 - Elsevier
Background To evaluate the cerebral metabolism in patients with heart failure (HF). Methods
One hundred and two HF patients were prospectively enrolled, who underwent gated 99m …