Exploiting molecular probes to perform near‐infrared fluorescence‐guided surgery
Near‐infrared (NIR) fluorescence imaging can provide real‐time navigation for surgeons to
discriminate boundaries between lesions and healthy tissue, which serves as a promising …
discriminate boundaries between lesions and healthy tissue, which serves as a promising …
Multiplex and in vivo optical imaging of discrete luminescent lanthanide complexes enabled by in situ Cherenkov radiation mediated energy transfer
Recently, we pioneered the application of Cherenkov radiation (CR) of radionuclides for the
in situ excitation of discrete Eu (III) and Tb (III) complexes. CR is produced by isotopes …
in situ excitation of discrete Eu (III) and Tb (III) complexes. CR is produced by isotopes …
[HTML][HTML] Pathways of glucagon secretion and trafficking in the pancreatic alpha cell: novel pathways, proteins, and targets for hyperglucagonemia
F Asadi, S Dhanvantari - Frontiers in Endocrinology, 2021 - frontiersin.org
Patients with diabetes mellitus exhibit hyperglucagonemia, or excess glucagon secretion,
which may be the underlying cause of the hyperglycemia of diabetes. Defective alpha cell …
which may be the underlying cause of the hyperglycemia of diabetes. Defective alpha cell …
[HTML][HTML] Differential morphological diagnosis of various forms of congenital hyperinsulinism in children
LB Mitrofanova, AA Perminova, DV Ryzhkova… - Frontiers in …, 2021 - frontiersin.org
Introduction Congenital hyperinsulinism (CHI) has diffuse (CHI-D), focal (CHI-F) and atypical
(CHI-A) forms. Surgical management depends on preoperative [18F]-DOPA PET/CT and …
(CHI-A) forms. Surgical management depends on preoperative [18F]-DOPA PET/CT and …
[HTML][HTML] Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin (9-39)
E Collado Camps, SAM van Lith, A Kip… - European Journal of …, 2023 - Springer
Purpose Exendin, an analogue of the glucagon-like peptide 1 (GLP1), is an excellent tracer
for molecular imaging of pancreatic beta cells and beta cell-derived tumours. The commonly …
for molecular imaging of pancreatic beta cells and beta cell-derived tumours. The commonly …
Imaging of insulinoma by targeting glucagonlike Peptide-1 receptor
Y Luo, X Chen - PET clinics, 2021 - pet.theclinics.com
Insulinoma is a rare neuroendocrine tumor arising from pancreatic b cells with an incidence
of 0.4 per 100,000 people per year. 1 It is the most common cause of endogenous …
of 0.4 per 100,000 people per year. 1 It is the most common cause of endogenous …
Exploring the GLP-1–GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography
E Manell, E Puuvuori, A Svensson, I Velikyan… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction Glucagon-like peptide-1 (GLP-1) increases insulin secretion from pancreatic
beta-cells and GLP-1 receptor (GLP-1R) agonists are widely used as treatment for type 2 …
beta-cells and GLP-1 receptor (GLP-1R) agonists are widely used as treatment for type 2 …
Design, synthesis and characterization of a fluorescently labeled functional analog of full-length human ghrelin
M Liu, EA Whitfield, LJ Fothergill, JB Furness… - Biochemical and …, 2020 - Elsevier
Human ghrelin receptor (GHSR) is a recognized prospective target in the diagnosis and
therapy of multiple cancer types. To gain a better understanding of this receptor signaling …
therapy of multiple cancer types. To gain a better understanding of this receptor signaling …
Chelation of Luminescent and Radioactive Lanthanides for Targeted In Vivo Bioimaging
K Martin - 2023 - search.proquest.com
Within the lanthanide series, elements such as europium, terbium, and lanthanum possess
luminescent or radioactive properties ideal for use as optical or nuclear imaging agents …
luminescent or radioactive properties ideal for use as optical or nuclear imaging agents …
[PDF][PDF] 胰高血糖素样肽-1 受体显像定位诊断胰岛素瘤的研究进展
罗亚平， 潘青青， 霍力， 李方 - Acta Biochimica et Biophysica Sinica, 2019 - academia.edu
摘要胰岛素瘤的诊断和手术治疗依赖于准确的影像学检查定位. 以胰腺β 细胞为靶点的胰高血糖
素样肽-1 受体(glucagon-like peptide-1 receptor, GLP-1 receptor) 显像是近年来建立的定位 …
素样肽-1 受体(glucagon-like peptide-1 receptor, GLP-1 receptor) 显像是近年来建立的定位 …