Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-
life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five …

Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …

Somatostatin receptor (SSTR) PET has demonstrated a significant improvement over
conventional imaging (CI) in patients with neuroendocrine tumors (NETs). SSTR PET should …

Abstract'See what you treat and treat what you see, at a molecular level', could be the motto
of theranostics. The concept implies diagnosis (imaging) and treatment of cells (usually …

Copper-64 (T1/2= 12.7 h) is a positron and beta-emitting isotope, with decay characteristics
suitable for both positron emission tomography (PET) imaging and radiotherapy of cancer …

Lutetium 177 (177Lu) DOTA-0-Tyr3-Octreotate (DOTATATE) peptide receptor radionuclide
therapy (PRRT) is an effective treatment for advanced gastroenteropancreatic …

Gastroenteropancreatic neuroendocrine neoplasms are a heterogenous group of rare
neoplasms that are increasingly being discovered, often incidentally, throughout the …

Simple Summary Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a
group of tumors with different clinical manifestations, various localizations in the human …

Neuroendocrine tumors (NETs) are a heterogeneous clinical entity with a broad range of
grade, pace of disease, functional status, and primary sites. Pathologic classification …

PET imaging has gained significant momentum in the last few years, especially in the area
of oncology, with an increasing focus on metal radioisotopes owing to their versatile …