[HTML][HTML] Radiopharmaceutical therapy in cancer: clinical advances and challenges

G Sgouros, L Bodei, MR McDevitt… - Nature reviews Drug …, 2020 - nature.com
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

Gold Complexes in Anticancer Therapy: From New Design Principles to Particle‐Based Delivery Systems

G Moreno‐Alcántar, P Picchetti… - Angewandte Chemie, 2023 - Wiley Online Library
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

[HTML][HTML] Insight into the Development of PET Radiopharmaceuticals for Oncology

J Lau, E Rousseau, D Kwon, KS Lin, F Bénard, X Chen - Cancers, 2020 - mdpi.com
While the development of positron emission tomography (PET) radiopharmaceuticals
closely follows that of traditional drug development, there are several key considerations in …

Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review

KA Morgan, SE Rudd, A Noor, PS Donnelly - Chemical Reviews, 2023 - ACS Publications
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Advanced materials and technologies for oral diseases

H Cui, Y You, GW Cheng, Z Lan, KL Zou… - … and Technology of …, 2023 - Taylor & Francis
Oral disease, as a class of diseases with very high morbidity, brings great physical and
mental damage to people worldwide. The increasing burden and strain on individuals and …

[HTML][HTML] Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) 18F-Radiopharmaceuticals

L Gower-Fry, T Kronemann, A Dorian, Y Pu… - Pharmaceuticals, 2021 - mdpi.com
The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules,
such as peptides, proteins and biologically relevant small molecules, has improved the …

Gastrin-releasing peptide receptor agonists and antagonists for molecular imaging of breast and prostate cancer: from pre-clinical studies to translational perspectives

J Gorica, MS De Feo, L Filippi… - Expert Review of …, 2022 - Taylor & Francis
Introduction Prostate and breast cancer represent a leading cause of cancer-related death
worldwide with a dramatic social and demographic impact. Gastrin-releasing peptide …

[HTML][HTML] Gastrin releasing peptide receptor targeted nano-graphene oxide for near-infrared fluorescence imaging of oral squamous cell carcinoma

R Li, R Gao, Y Wang, Z Liu, H Xu, A Duan, F Zhang… - Scientific reports, 2020 - nature.com
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor that occurs in
the oral mucosa. Pathological biopsy is still the current gold standard for OSCC diagnosis; …

[HTML][HTML] Bombesin receptor family activation and CNS/neural tumors: review of evidence supporting possible role for novel targeted therapy

TW Moody, L Lee, I Ramos-Alvarez… - Frontiers in …, 2021 - frontiersin.org
G-protein-coupled receptors (GPCRs) are increasingly being considered as possible
therapeutic targets in cancers. Activation of GPCR on tumors can have prominent growth …

[HTML][HTML] Non-conventional and investigational PET radiotracers for breast cancer: a systematic review

M Balma, V Liberini, M Racca, R Laudicella… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is one of the most common malignancies in women, with high morbidity and
mortality rates. In breast cancer, the use of novel radiopharmaceuticals in nuclear medicine …