[HTML][HTML] RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …
investigated as therapeutic targets over the last decades, motivated by their multiple …
[HTML][HTML] SARS-CoV-2: receptor and co-receptor Tropism Probability
The recent pandemic which arose from China, is caused by a pathogenic virus named
“severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2)”. Its rapid global …
“severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2)”. Its rapid global …
[HTML][HTML] Construction of nanomaterials as contrast agents or probes for glioma imaging
Malignant glioma remains incurable largely due to the aggressive and infiltrative nature, as
well as the existence of blood–brain-barrier (BBB). Precise diagnosis of glioma, which aims …
well as the existence of blood–brain-barrier (BBB). Precise diagnosis of glioma, which aims …
[HTML][HTML] Role of 2-[18F]FDG as a Radiopharmaceutical for PET/CT in Patients with COVID-19: A Systematic Review
S Annunziata, RC Delgado Bolton, CH Kamani… - Pharmaceuticals, 2020 - mdpi.com
Some recent studies evaluated the role of fluorine-18 fluorodeoxyglucose (2-[18F] FDG) as a
radiopharmaceutical for positron emission tomography/computed tomography (PET/CT) …
radiopharmaceutical for positron emission tomography/computed tomography (PET/CT) …
[HTML][HTML] Age-related dynamics of lung-resident memory CD8+ T cells in the age of COVID-19
Following respiratory viral infections or local immunizations, lung resident-memory T cells (T
RM) of the CD8 lineage provide protection against the same pathogen or related pathogens …
RM) of the CD8 lineage provide protection against the same pathogen or related pathogens …
[HTML][HTML] It's time to shift the paradigm: translation and clinical application of non-αvβ3 integrin targeting radiopharmaceuticals
Simple Summary Cancer cells often present a different set of proteins on their surface than
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …
αVβ6 Integrin: An Intriguing Target for COVID‐19 and Related Diseases
K Bugatti - ChemBioChem, 2021 - Wiley Online Library
The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global
health emergency. As the novel coronavirus is continuing to spread over the world, the need …
health emergency. As the novel coronavirus is continuing to spread over the world, the need …
[HTML][HTML] Positron emission tomography in the COVID-19 pandemic era
C Jin, X Luo, S Qian, K Zhang, Y Gao, R Zhou… - European journal of …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has become a major public health problem
worldwide since its outbreak in 2019. Currently, the spread of COVID-19 is far from over, and …
worldwide since its outbreak in 2019. Currently, the spread of COVID-19 is far from over, and …
[HTML][HTML] Optimized serum stability and specificity of an αvβ6 integrin-binding peptide for tumor targeting
The integrin αvβ6 is an antigen expressed at low levels in healthy tissue but upregulated
during tumorigenesis, which makes it a promising target for cancer imaging and therapy …
during tumorigenesis, which makes it a promising target for cancer imaging and therapy …
Advances and Challenges in Molecular Imaging of Viral Infections
CY Lau, N Martinez-Orengo, A Lyndaker… - The Journal of …, 2023 - academic.oup.com
Molecular imaging of viral infection, using a variety of advanced imaging techniques such as
optical and nuclear imaging, can and has been used for direct visualization of the virus as …
optical and nuclear imaging, can and has been used for direct visualization of the virus as …