Simple Summary Beyond its pre-eminent role in the context of tumor cell growth as well as
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …

A growing number of copper (II) complexes have been identified as suitable candidates for
biomedical applications. Here, we show that the biocompatibility and stability of copper (II) …

Non-invasive PET imaging of CXCR4 expression in cancer and inflammation as well as
CXCR4-targeted radioligand therapy (RLT) have recently found their way into clinical …

Chemokine receptors are important components of cellular signaling and play a critical role
in directing leukocytes during inflammatory reactions. Their importance extends to numerous …

Introduction The chemokine receptor CXCR4 has been shown to be over-expressed in
multiple types of cancer and is usually associated with aggressive phenotypes and poor …

Ethylene cross-bridged tetraazamacrocycles are known to produce kinetically stable
transition metal complexes that can act as robust oxidation catalysts under harsh aqueous …

CXC motif chemokine receptor 4 (CXCR4) plays a key role in various physiological
functions, such as immune processes and disease development, and can influence …

Therapeutic response is evaluated using the diameter of tumors and quantitative parameters
of 2-[18F] fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET). Tumor …

This article presents the controlled synthesis of a rare example of C, C′-linked bis-cyclam
architecture in mild conditions through the “bis-aminal” route previously used for the …

CXC chemokine receptor type 4 (CXCR4), also known as fusin or CD184, is a 7-
transmembrane helix G-protein-coupled receptor that is encoded by the CXCR4 gene …