ImmunoPET: concept, design, and applications
W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
[HTML][HTML] Nano carrier drug delivery systems for the treatment of neuropsychiatric disorders: Advantages and limitations
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …
people. Various drugs are used for its treatment, although no effective therapy has been …
Hyperosmolar blood–brain barrier opening using intra-arterial injection of hyperosmotic mannitol in mice under real-time MRI guidance
The blood–brain barrier (BBB) is the main obstacle to the effective delivery of therapeutic
agents to the brain, compromising treatment efficacy for a variety of neurological disorders …
agents to the brain, compromising treatment efficacy for a variety of neurological disorders …
Dendrimer as a momentous tool in tissue engineering and regenerative medicine
A Shaikh, P Kesharwani, V Gajbhiye - Journal of Controlled Release, 2022 - Elsevier
Dendrimers have been comprehensively used for cargo delivery, nucleic acid delivery
(genes, miRNA/siRNAs), delivery of macromolecules, and other various biomedical …
(genes, miRNA/siRNAs), delivery of macromolecules, and other various biomedical …
Advances in drug delivery technology for the treatment of glioblastoma multiforme
Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …
[HTML][HTML] Multimodal molecular imaging in drug discovery and development
I Vermeulen, EM Isin, P Barton, B Cillero-Pastor… - Drug discovery today, 2022 - Elsevier
In addition to individual imaging techniques, the combination and integration of several
imaging techniques, so-called multimodal imaging, can provide large amounts of …
imaging techniques, so-called multimodal imaging, can provide large amounts of …
Current approaches to facilitate improved drug delivery to the central nervous system
M Markowicz-Piasecka, P Darłak, A Markiewicz… - European Journal of …, 2022 - Elsevier
Although many pharmaceuticals have therapeutic potentials for central nervous system
(CNS) diseases, few of these agents have been effectively administered. It is due to the fact …
(CNS) diseases, few of these agents have been effectively administered. It is due to the fact …
The role of 89Zr-immuno-PET in navigating and derisking the development of biopharmaceuticals
GAMS van Dongen, W Beaino… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The identification of molecular drivers of disease and the compelling rise of biotherapeutics
have impacted clinical care but have also come with challenges. Such therapeutics include …
have impacted clinical care but have also come with challenges. Such therapeutics include …
[HTML][HTML] ImmunoPET: antibody-based PET imaging in solid tumors
R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …
combining the high sensitivity of PET with the specific targeting ability of monoclonal …
[HTML][HTML] Brain delivery of single-domain antibodies: A focus on VHH and VNAR
E Pothin, D Lesuisse, P Lafaye - Pharmaceutics, 2020 - mdpi.com
Passive immunotherapy, ie, treatment with therapeutic antibodies, has been increasingly
used over the last decade in several diseases such as cancers or inflammation. However …
used over the last decade in several diseases such as cancers or inflammation. However …