ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[HTML][HTML] Current Perspectives on 89Zr-PET Imaging

JK Yoon, BN Park, EK Ryu, YS An, SJ Lee - International Journal of …, 2020 - mdpi.com
89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …

State of the art in radiolabeling of antibodies with common and uncommon radiometals for preclinical and clinical immuno-PET

M Chomet, GAMS van Dongen… - Bioconjugate chemistry, 2021 - ACS Publications
Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

Functional organic dyes for health‐related applications

W Cheng, H Chen, C Liu, C Ji, G Ma, M Yin - View, 2020 - Wiley Online Library
Nowadays, photo‐based diagnosis and treatment techniques have been the focus in health‐
related fields. Organic dyes with delicately designed structures and tunable optical …

[HTML][HTML] Affibody molecules as targeting vectors for PET imaging

V Tolmachev, A Orlova - Cancers, 2020 - mdpi.com
Affibody molecules are small (58 amino acids) engineered scaffold proteins that can be
selected to bind to a large variety of proteins with a high affinity. Their small size and high …

[HTML][HTML] ImmunoPET: antibody-based PET imaging in solid tumors

R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

[HTML][HTML] Triggering anti-GBM immune response with EGFR-mediated photoimmunotherapy

J Mączyńska, F Raes, C Da Pieve, S Turnock… - BMC medicine, 2022 - Springer
Background Surgical resection followed by chemo-radiation postpones glioblastoma (GBM)
progression and extends patient survival, but these tumours eventually recur. Multimodal …

[HTML][HTML] Radiometals in Imaging and Therapy: Highlighting Two Decades of Research

S Sharma, MK Pandey - Pharmaceuticals, 2023 - mdpi.com
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

[HTML][HTML] PET and SPECT imaging of the EGFR family (RTK class I) in oncology

SS Rinne, A Orlova, V Tolmachev - International journal of molecular …, 2021 - mdpi.com
The human epidermal growth factor receptor family (EGFR-family, other designations: HER
family, RTK Class I) is strongly linked to oncogenic transformation. Its members are …

[HTML][HTML] Advances in nuclear medicine-based molecular imaging in head and neck squamous cell carcinoma

D Li, X Li, J Zhao, F Tan - Journal of Translational Medicine, 2022 - Springer
Head and neck squamous cell carcinomas (HNSCCs) are often aggressive, making
advanced disease very difficult to treat using contemporary modalities, such as surgery …