Advances in multimodal data fusion in neuroimaging: Overview, challenges, and novel orientation
Multimodal fusion in neuroimaging combines data from multiple imaging modalities to
overcome the fundamental limitations of individual modalities. Neuroimaging fusion can …
overcome the fundamental limitations of individual modalities. Neuroimaging fusion can …
[HTML][HTML] Leveraging Technology to Diagnose Alzheimer's Disease: A Systematic Review and Meta-Analysis
CS Kruse, ME Mileski, R Wilkinson, B Hock, R Samson… - Healthcare, 2023 - mdpi.com
Background: About 50 million people worldwide suffered from dementia in 2018—two-thirds
of those with Alzheimer's disease (AD). By 2050, this number is expected to rise to 152 …
of those with Alzheimer's disease (AD). By 2050, this number is expected to rise to 152 …
Metabolic syndrome and its components in relation to in vivo brain amyloid and neurodegeneration in late middle age
Metabolic syndrome (MetS) is associated with dementia, but it is unclear whether MetS is
related to Alzheimer's disease (AD). We investigated the association of MetS with brain …
related to Alzheimer's disease (AD). We investigated the association of MetS with brain …
Pre-diabetes, but not type 2 diabetes, is related to brain amyloid in late middle-age
JA Luchsinger, P Palta, B Rippon… - Journal of …, 2020 - content.iospress.com
Background: Type 2 diabetes is a dementia risk factor, but its relation to Alzheimer's disease
(AD), the most common cause of dementia, is unclear. Objective: Our primary objective was …
(AD), the most common cause of dementia, is unclear. Objective: Our primary objective was …
Sex differences in in vivo tau neuropathology in a multiethnic sample of late middle-aged adults
It is unclear whether women have higher brain tau pathology. The objective of this study was
to examine whether women have higher tau burden than men, and whether tau differences …
to examine whether women have higher tau burden than men, and whether tau differences …
Topographical overlapping of the amyloid-β and tau pathologies in the default mode network predicts Alzheimer's disease with higher specificity
SH Hojjati, F Feiz, S Ozoria… - Journal of …, 2021 - content.iospress.com
Background: While amyloid-ß (Aß) plaques and tau tangles are the well-recognized
pathologies of Alzheimer's disease (AD), they are more often observed in healthy individuals …
pathologies of Alzheimer's disease (AD), they are more often observed in healthy individuals …
[HTML][HTML] Distinct and joint effects of low and high levels of Aβ and tau deposition on cortical thickness
Alzheimer's disease (AD) is defined by the presence of Amyloid-β (Aβ), tau, and
neurodegeneration (ATN framework) in the human cerebral cortex. Yet, prior studies have …
neurodegeneration (ATN framework) in the human cerebral cortex. Yet, prior studies have …
Sex differences in in vivo Alzheimer's disease neuropathology in late middle-aged Hispanics
JA Luchsinger, P Palta, B Rippon… - Journal of …, 2020 - content.iospress.com
Background: Females may have a higher risk of dementia than males. It is not clear if sex
differences in Alzheimer's disease (AD) neuropathology explain the higher risk of dementia …
differences in Alzheimer's disease (AD) neuropathology explain the higher risk of dementia …
The laterality of early age-related hearing loss and brain β-amyloid
Objective: Worse hearing was linked to higher brain β-amyloid, a pathologic hallmark of
Alzheimer's disease, in a recent study. We analyze the associations between β-amyloid and …
Alzheimer's disease, in a recent study. We analyze the associations between β-amyloid and …
In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults
The relationship between tau deposition and cognitive decline in cognitively healthy older
adults is still unclear. The tau PET tracer 18 F-MK-6240 has shown favorable imaging …
adults is still unclear. The tau PET tracer 18 F-MK-6240 has shown favorable imaging …