Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

The vascular interface of the brain, known as the blood–brain barrier (BBB), is understood to
maintain brain function in part via its low transcellular permeability,–. Yet, recent studies …

Neuroinflammation is an inflammatory response in the brain and spinal cord, which can
involve the activation of microglia and astrocytes. It is a common feature of many central …

The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is predominately localized to the outer mitochondrial membrane in …

Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however,
its exact role in vivo is yet to be fully understood. PET imaging enables investigation …

Over the last 30 years, the 18-kDa TSPO protein has been considered as the PET imaging
biomarker of reference to measure increased neuroinflammation. Generally assumed to …

Neuroinflammation and cell death are among the common symptoms of many central
nervous system diseases and injuries. Neuroinflammation and programmed cell death of the …

Neuroinflammation is a hallmark of ischemic stroke, which is a leading cause of death and
long‐term disability. Understanding the exact cellular signaling pathways that initiate and …

The translocator protein 18kDa (TSPO) is expressed in the outer mitochondrial membrane
and is implicated in several functions, including cholesterol transport and steroidogenesis …