Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Until recently, it has been challenging to engage Wall Street and large pharmaceutical
companies in radiopharmaceutical opportunities. The modest economic prospects of most …

Radiopharmaceutical therapy using 177Lu-prostate-specific membrane antigen (PSMA) is
an effective prostate cancer treatment that was recently approved by the US Food and Drug …

New fluorine‐18 radiochemistry has been extensively reviewed in recent years, and this
chapter focuses on highlighting key new methods utilizing [18F] F‐as a reagent for the …

Following progress in modern medicine, advances have been made in diagnosis and
treatment tools. Multifunctional nanomaterials that combine therapeutic and diagnostic …

Sorgfältig aktualisierte Neuauflage dieses wegweisenden Referenzwerk der
radiopharmazeutischen Wissenschaften Die 2. Auflage des Handbook of …

Gallium‐68 has seen the largest growth in nuclear medicine usage of any isotope over the
past 10 years. To design an ideal chelator for 68Ga, a range of criteria need to be met: fast …

Clinically, the growth in radiotherapy has been in the use of targeted radiotherapeutics for
the treatment of cancer, as shown in this chapter, but other emerging applications are also …

The novel chelator, NOTET, a tetrazole analogue of NOTA, was successfully synthesised via
the tris-alkylation of TACN with chloroacetonitrile followed by [3+ 2] cycloaddition using …

In the last 3 decades, the development of positron emission tomography-computed
tomography (PET-CT)/positron emission tomography-magnetic resonance (PET-MR) …