Aptamer-based technology for radionuclide targeted imaging and therapy: A promising weapon against cancer
L Filippi, O Bagni, C Nervi - Expert Review of Medical Devices, 2020 - Taylor & Francis
Introduction aptamers are short artificial, single-strand oligonucleotide sequences (DNA,
RNA or modified RNA), capable of binding to biological molecules with high affinity and …
RNA or modified RNA), capable of binding to biological molecules with high affinity and …
Therapeutic Potential of Aptamer–Protein Interactions
AS Shraim, BA Abdel Majeed… - ACS Pharmacology & …, 2022 - ACS Publications
Aptamers are single-stranded oligonucleotides (RNA or DNA) with a typical length between
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …
The first-in-human whole-body dynamic pharmacokinetics study of Aptamer
Serving as targeting ligands, aptamers have shown promise in precision medicine.
However, the lack of knowledge of the biosafety and metabolism patterns in the human body …
However, the lack of knowledge of the biosafety and metabolism patterns in the human body …
[HTML][HTML] Aptamers: Cutting edge of cancer therapies
S Shigdar, B Schrand, PH Giangrande… - Molecular Therapy, 2021 - cell.com
The development of an aptamer-based therapeutic has rapidly progressed following the first
two reports in the 1990s, underscoring the advantages of aptamer drugs associated with …
two reports in the 1990s, underscoring the advantages of aptamer drugs associated with …
Generation of CD44-specific aptamers for targeted approaches in the treatment of pancreatic cancer
J Peterhansl - 2023 - edoc.ub.uni-muenchen.de
Pancreatic ductal adenocarcinoma (PDAC) has become one of the leading causes of cancer
related death worldwide due to its aggressive local behavior and early metastatic spread …
related death worldwide due to its aggressive local behavior and early metastatic spread …