Sickle-cell disease is an autosomal recessive genetic disorder of hemoglobin that causes
systemic damage. Hypoxia is the main actor of sickle-cell disease. It initiates acutely the …

Introduction: Venous thromboembolism (VTE) is a common comorbid condition found in
sickle cell disease (SCD) and is associated with increased mortality for adults with SCD. The …

Introduction The outcomes of pulmonary embolism (PE) in sickle cell disease (SCD) are
poorly established in the literature. This study examined the prevalence and outcomes of …

Pulmonary hypertension (PH) in adults with sickle cell disease (SCD) is associated with
early mortality. Chronic thromboembolic PH (CTEPH) is an important complication and …

Background Pulmonary complications are common in sickle cell disease (SCD) and can
mimic pulmonary embolisms (PEs), leading to potential overuse of computed tomography …

Sickle cell disease is a debilitating hematologic process that affects the entire body. Disease
manifestations in the abdomen most commonly result from vaso-occlusion, hemolysis, or …

Individuals living with sickle cell disease (SCD) are at an increased risk of venous thrombo‐
embolism (VTE) including pulmonary embolisms (PEs). There is a high mortality associated …

Background Sickle cell disease (SCD) is a genetic hematological disorder associated with
severe complications, such as vaso-occlusive crises, acute chest syndrome (ACS), and an …

Purpose Acute chest syndrome (ACS) is secondary to occlusion of the pulmonary
vasculature and a potentially life-threatening complication of sickle cell disease (SCD). Dual …

METHODS Under expedited review from our local IRB, this HIPAA-compliant case-control
study selected consecutive sickle cell patients who had undergone a CT for pulmonary …