[HTML][HTML] Somatostatin analogues in the treatment of neuroendocrine tumors: past, present and future

AK Stueven, A Kayser, C Wetz, H Amthauer… - International journal of …, 2019 - mdpi.com
In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased.
Due to the slow-growing nature of these tumors and the lack of early symptoms, most cases …

[HTML][HTML] Somatostatin receptor PET ligands-the next generation for clinical practice

E Pauwels, F Cleeren, G Bormans… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Somatostatin receptors (SSTRs) are variably expressed by a variety of malignancies. Using
radiolabeled somatostatin analogs (SSAs), the presence of SSTRs on tumor cells may be …

Albumin binder–conjugated fibroblast activation protein inhibitor radiopharmaceuticals for cancer therapy

M Xu, P Zhang, J Ding, J Chen, L Huo… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Fibroblast activation protein (FAP) has become an attractive target for diagnosis and
therapy, and a series of FAP inhibitor (FAPI)–based radiotracers has been developed and …

[HTML][HTML] Radiolabeled somatostatin analogs—a continuously evolving class of radiopharmaceuticals

M Fani, R Mansi, GP Nicolas, D Wild - Cancers, 2022 - mdpi.com
Simple Summary Somatostatin receptors (SSTs) are of particular interest in oncology
because these proteins are overexpressed on the cell membranes of different human …

Imaging-guided targeted radionuclide tumor therapy: From concept to clinical translation

J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …

Peptide receptor radionuclide therapy in grade 3 neuroendocrine neoplasms: safety and survival analysis in 69 patients

J Zhang, HR Kulkarni, A Singh, K Niepsch… - Journal of Nuclear …, 2019 - Soc Nuclear Med
To date, limited data are available concerning peptide receptor radionuclide therapy (PRRT)
of grade 3 (G3) neuroendocrine neoplasms (NENs) with a Ki-67 proliferation index of …

Fatty acid-conjugated radiopharmaceuticals for fibroblast activation protein-targeted radiotherapy

P Zhang, M Xu, J Ding, J Chen, T Zhang, L Huo… - European Journal of …, 2022 - Springer
Introduction Radiopharmaceuticals that target cancer-associated fibroblasts (CAFs) have
become an increasingly attractive strategy for cancer theranostics. Recently, a series of …

[HTML][HTML] A review on curability of cancers: more efforts for novel therapeutic options are needed

S Wang, Y Liu, Y Feng, J Zhang, J Swinnen, Y Li, Y Ni - Cancers, 2019 - mdpi.com
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …

177Lu-DOTATATE for the treatment of gastroenteropancreatic neuroendocrine tumors

S Das, T Al-Toubah, G El-Haddad… - Expert review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: 177Lutetium-[DOTA°, Tyr3] octreotate (177Lu-DOTATATE) is a
type of peptide receptor radionuclide therapy that garnered FDA approval in January 2018 …

[HTML][HTML] Molecular imaging and radionuclide therapy of pheochromocytoma and paraganglioma in the era of genomic characterization of disease subgroups

D Taïeb, A Jha, G Treglia… - Endocrine-related cancer, 2019 - erc.bioscientifica.com
In recent years, advancement in genetics has profoundly helped to gain a more
comprehensive molecular, pathogenic, and prognostic picture of pheochromocytomas and …