Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

Innovations in nuclear imaging instrumentation: Cerenkov imaging

R Tamura, EC Pratt, J Grimm - Seminars in nuclear medicine, 2018 - Elsevier
Cerenkov luminescence (CL) is blue glow light produced by charged subatomic particles
travelling faster than the phase velocity of light in a dielectric medium such as water or …

Dual cherenkov radiation-induced near-infrared luminescence imaging and photodynamic therapy toward tumor resection

V Lioret, PS Bellaye, C Arnould, B Collin… - Journal of Medicinal …, 2020 - ACS Publications
Cherenkov radiation (CR), the blue light seen in nuclear reactors, is emitted by some
radiopharmaceuticals. This study showed that (1) a portion of CR could be transferred in the …

Light‐Sensitive Phenacyl Crosslinked Dextran Hydrogels for Controlled Delivery

TG Brevé, M Filius, S Weerdenburg… - … A European Journal, 2022 - Wiley Online Library
Stimuli‐responsive soft materials enable controlled release of loaded drug molecules and
biomolecules. Controlled release of potent chemotherapeutic or immunotherapeutic agents …

[HTML][HTML] In vitro irradiation of doxorubicin with 18F-FDG Cerenkov radiation and its potential application as a theragnostic system.

HA Quintos-Meneses, L Aranda-Lara… - … of Photochemistry and …, 2020 - Elsevier
Doxorubicin (DOX), an effective chemotherapeutic agent, has a wide excitation band
centred at 480 nm. Cerenkov radiation (CR) is considered an internal light source in …

A Multimodal Theranostic System Prepared from High-Density Lipoprotein Carrier of Doxorubicin and 177Lu

HA Quintos-Meneses, L Aranda-Lara… - Journal of …, 2021 - ingentaconnect.com
Recently, it was demonstrated that doxorubicin (Dox. HCl), a chemotherapeutic agent, could
be photoactivated by Cerenkov radiation (CR). The objective of the present work was to …

Design of Cerenkov radiation–assisted photoactivation of TiO2 nanoparticles and reactive oxygen species generation for cancer treatment

S Kavadiya, P Biswas - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
The use of Cerenkov radiation to activate nanoparticles in situ was recently shown to control
cancerous tumor growth. Although the methodology has been demonstrated to work, to …

Shining a light on bioorthogonal photochemistry for polymer science

NRB Boase - Macromolecular Rapid Communications, 2020 - Wiley Online Library
Bioorthogonal chemistry is revolutionizing the fields of biological chemistry and
nanomedicine, providing tools to actively probe and perturb native biochemical processes …

[HTML][HTML] Prior compensation algorithm for Cerenkov luminescence tomography from single-view measurements

L Wang, X He, J Yu - Frontiers in Oncology, 2021 - frontiersin.org
Cerenkov luminescence tomography (CLT) has attracted much attention because of the
wide clinically-used probes and three-dimensional (3D) quantification ability. However, due …

Targeted photodynamic therapy using reconstituted high-density lipoproteins as rhodamine transporters

MA Ávila-Sánchez, K Isaac-Olivé, L Aranda-Lara… - Photodiagnosis and …, 2022 - Elsevier
Reconstituted high-density lipoprotein (rHDL) nanoparticles are excellent transporters of
molecules and very useful for targeted therapy as they specifically recognize the scavenger …