ImmunoPET: concept, design, and applications
W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …
[HTML][HTML] Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade
G Crișan, NS Moldovean-Cioroianu… - International Journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …
imaging of several metabolic processes, blood flow measurements, regional chemical …
[HTML][HTML] Monoclonal antibody-based molecular imaging strategies and theranostic opportunities
N Dammes, D Peer - Theranostics, 2020 - ncbi.nlm.nih.gov
Molecular imaging modalities hold great potential as less invasive techniques for diagnosis
and management of various diseases. Molecular imaging combines imaging agents with …
and management of various diseases. Molecular imaging combines imaging agents with …
[HTML][HTML] Current Perspectives on 89Zr-PET Imaging
JK Yoon, BN Park, EK Ryu, YS An, SJ Lee - International Journal of …, 2020 - mdpi.com
89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …
[HTML][HTML] Radiolabeled antibodies for cancer imaging and therapy
Simple Summary Monoclonal antibodies (mAbs) have the ability to specifically target tumor-
cell antigens. This unique property has led to their use in the delivery of radioisotopes to …
cell antigens. This unique property has led to their use in the delivery of radioisotopes to …
CD38-targeted immuno-PET of multiple myeloma: from xenograft models to first-in-human imaging
Background Current measurements of multiple myeloma disease burden are suboptimal.
Daratumumab is a monoclonal antibody that targets CD38, an antigen expressed on nearly …
Daratumumab is a monoclonal antibody that targets CD38, an antigen expressed on nearly …
EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer
The anti-HER2 antibody trastuzumab is standard care for advanced esophagogastric (EG)
cancer with ERBB2 (HER2) amplification or overexpression, but intrinsic and acquired …
cancer with ERBB2 (HER2) amplification or overexpression, but intrinsic and acquired …
First-in-human human epidermal growth factor receptor 2–targeted imaging using 89Zr-Pertuzumab PET/CT: dosimetry and clinical application in patients with breast …
In what we believe to be a first-in-human study, we evaluated the safety and dosimetry of
89Zr-pertuzumab PET/CT for human epidermal growth factor receptor 2 (HER2)–targeted …
89Zr-pertuzumab PET/CT for human epidermal growth factor receptor 2 (HER2)–targeted …
[HTML][HTML] Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
Human epidermal growth factor receptor 2 (HER2) gene amplification and/or protein
overexpression in tumors is a prerequisite for initiation of trastuzumab therapy. Although …
overexpression in tumors is a prerequisite for initiation of trastuzumab therapy. Although …
[HTML][HTML] ImmunoPET: antibody-based PET imaging in solid tumors
R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …
combining the high sensitivity of PET with the specific targeting ability of monoclonal …