[HTML][HTML] Radiopharmaceutical therapy in cancer: clinical advances and challenges

G Sgouros, L Bodei, MR McDevitt… - Nature reviews Drug …, 2020 - nature.com
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

[HTML][HTML] Two decades of SPECT/CT–the coming of age of a technology: an updated review of literature evidence

O Israel, O Pellet, L Biassoni, D De Palma… - European journal of …, 2019 - Springer
Purpose Single-photon emission computed tomography (SPECT) combined with computed
tomography (CT) was introduced as a hybrid SPECT/CT imaging modality two decades ago …

[HTML][HTML] Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer

C Müller, CA Umbricht, N Gracheva, VJ Tschan… - European journal of …, 2019 - Springer
Purpose The prostate-specific membrane antigen (PSMA) has emerged as an interesting
target for radionuclide therapy of metastasized castration-resistant prostate cancer …

PSMA-targeted radiopharmaceuticals for imaging and therapy

HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

Review on 99mTc radiopharmaceuticals with emphasis on new advancements

A Duatti - Nuclear Medicine and Biology, 2021 - Elsevier
Rapid imaging acquisition, high spatial resolution and sensitivity, powered by
advancements in solid-state detector technology, are significantly changing the perspective …

Advances in Prostate‐Specific Membrane Antigen (PSMA)‐Targeted Phototheranostics of Prostate Cancer

H Wang, Z He, XA Liu, Y Huang, J Hou… - Small …, 2022 - Wiley Online Library
With the advent of the era of precision medicine, prostate‐specific membrane antigen
(PSMA)‐targeted theranostic strategies have had a profound impact on prostate cancer …

[HTML][HTML] Third-line treatment and 177Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review

FE von Eyben, G Roviello, T Kiljunen… - European journal of …, 2018 - Springer
Aims There is a controversy as to the relative efficacy of 177 Lu prostate specific membrane
antigen (PSMA) radioligand therapy (RLT) and third-line treatment for patients with …

Intraindividual comparison of 18F-PSMA-1007 and 18F-DCFPyL PET/CT in the prospective evaluation of patients with newly diagnosed prostate carcinoma: a pilot …

FL Giesel, L Will, I Lawal, T Lengana… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The introduction of 18F-labeled prostate-specific membrane antigen (PSMA)–targeted
PET/CT tracers, first 18F-DCFPyL (2-(3-{1-carboxy-5-[(6-18F-fluoro-pyridine-3-carbonyl) …

A perspective on the evolving story of PSMA biology, PSMA-based imaging, and endoradiotherapeutic strategies

DS O'Keefe, DJ Bacich, SS Huang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
In this review, we cover the evolution of knowledge on the biology of prostate-specific
membrane antigen (PSMA) and its translation to therapy. The usual key to discovery is a …

[HTML][HTML] A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging

J Zhang, A Rakhimbekova, X Duan, Q Yin… - Nature …, 2021 - nature.com
Surgery is an efficient way to treat localized prostate cancer (PCa), however, it is challenging
to demarcate rapidly and accurately the tumor boundary intraoperatively, as existing tumor …