[HTML][HTML] Implications of physics, chemistry and biology for dosimetry calculations using theranostic pairs

C Miller, J Rousseau, CF Ramogida, A Celler… - Theranostics, 2022 - ncbi.nlm.nih.gov
Theranostics is an emerging paradigm that combines imaging and therapy in order to
personalize patient treatment. In nuclear medicine, this is achieved by using …

Preclinical Evaluation of [64Cu]NOTA-CP01 as a PET Imaging Agent for Metastatic Esophageal Squamous Cell Carcinoma

T Peng, X Wang, Z Li, L Bi, J Gao, M Yang… - Molecular …, 2021 - ACS Publications
Targeting metastatic esophageal squamous cell carcinoma (ESCC) has been a challenge in
clinical practice. Emerging evidence demonstrates that CXC chemokine receptor 4 (CXCR4) …

Development of a theranostic convergence bioradiopharmaceutical for immuno-PET based radioimmunotherapy of L1CAM in cholangiocarcinoma model

IH Song, MS Jeong, HJ Hong, JI Shin, YS Park… - Clinical Cancer …, 2019 - AACR
Purpose: Cholangiocarcinoma is a malignancy of bile duct with a poor prognosis.
Conventional chemotherapy and radiotherapy are generally ineffective, and surgical …

Advances and challenges in immunoPET methodology

P Mohr, J Van Sluis, MN Lub-de Hooge… - Frontiers in Nuclear …, 2024 - frontiersin.org
Immuno-positron emission tomography (immunoPET) enables imaging of specific targets
that play a role in targeted therapy and immunotherapy, such as antigens on cell …

[HTML][HTML] An abbreviated therapy-dosimetric equation for the companion diagnostic/therapeutic [64/67Cu]Cu-SARTATE

E Laffon, H de Clermont, R Marthan - EJNMMI research, 2021 - Springer
In a preclinical model of neuroblastoma, Dearling et al. recently demonstrated the potential
interest for a theranostic approach of [64/67Cu] Cu-SARTATE for the detection and treatment …

Estimation of Cumulative Activity of 177Lu-Cetuximab from a Single Diagnostic 64Cu-Cetuximab Scan

E Laffon, R Marthan - Cancer Biotherapy & Radiopharmaceuticals, 2022 - liebertpub.com
Background: This study aimed at investigating whether a single diagnostic 64Cu-cetuximab
scan might predict therapeutic 177Lu-cetuximab cumulative activity in a preclinical study …

Preclinical SPECT and SPECT-CT in oncology

BL Franc, Y Seo, R Flavell, CM Aparici - Molecular Imaging in Oncology, 2020 - Springer
Molecular imaging enables both spatial and temporal understanding of the complex biologic
systems underlying carcinogenesis and malignant spread. Single-photon emission …