The role of neuroimaging in Parkinson's disease

NSR Bidesi, I Vang Andersen… - Journal of …, 2021 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of people
worldwide. Two hallmarks of PD are the accumulation of alpha‐synuclein and the loss of …

Brain imaging with near-infrared fluorophores

H Wang, X Mu, J Yang, Y Liang, XD Zhang… - Coordination Chemistry …, 2019 - Elsevier
As the centralized control system of the body, the brain is a complex organ of the utmost
importance that even the most minor disorder and trauma can cause inestimable harm …

[HTML][HTML] Propolis as a potential disease-modifying strategy in Parkinson's disease: cardioprotective and neuroprotective effects in the 6-OHDA rat model

V C. Gonçalves, D JLL Pinheiro, T de la Rosa… - Nutrients, 2020 - mdpi.com
Patients with Parkinson's disease (PD) manifest nonmotor and motor symptoms. Autonomic
cardiovascular dysregulation is a common nonmotor manifestation associated with …

Autonomic dysfunction in Parkinson disease and animal models

JM Metzger, ME Emborg - Clinical Autonomic Research, 2019 - Springer
Parkinson disease has traditionally been classified as a movement disorder, despite
patients' accounts of diverse symptoms stemming from impairments in numerous body …

The class II histone deacetylases as therapeutic targets for Parkinson's disease

M Mazzocchi, LM Collins, AM Sullivan… - Neuronal …, 2020 - portlandpress.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by
specific motor impairments. The neuropathological hallmarks of PD include progressive …

The future of cardiac molecular imaging

G Farber, KE Boczar, CC Wiefels, JGE Zelt… - Seminars in nuclear …, 2020 - Elsevier
Molecular imaging with positron emission tomography (PET) and single-photon emission
computed tomography (SPECT) serves numerous applications in clinical cardiology and …

Radiotracers for imaging of Parkinson's disease

NA Gharibkandi, SJ Hosseinimehr - European journal of medicinal …, 2019 - Elsevier
Radiotracers along with single photon emission computed tomography (SPECT) and
positron emission computed tomography (PET) instruments have led to significant advances …

Long-term trends in myocardial sympathetic innervation and function in synucleinopathies

G Lamotte, C Holmes, T Wu, DS Goldstein - Parkinsonism & related …, 2019 - Elsevier
Introduction Parkinson disease (PD), pure autonomic failure (PAF), and multiple system
atrophy (MSA) are characterized by intra-cerebral deposition of the protein alpha-synuclein …

Imaging the autonomic nervous system in Parkinson's disease

K Knudsen, P Borghammer - Current neurology and neuroscience reports, 2018 - Springer
Abstract Purpose of Review Patients with Parkinson's disease (PD) often display
gastrointestinal and genitourinary autonomic symptoms years or even decades prior to …

[HTML][HTML] Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements

X Chen, T Kudo, C Lapa, A Buck, T Higuchi - Journal of Neural …, 2020 - Springer
The norepinephrine transporter (NET) is a major target for the evaluation of the cardiac
sympathetic nerve system in patients with heart failure and Parkinson's disease. It is also …