Application of the 4-D XCAT phantoms in biomedical imaging and beyond
The four-dimensional (4-D) eXtended CArdiac-Torso (XCAT) series of phantoms was
developed to provide accurate computerized models of the human anatomy and physiology …
developed to provide accurate computerized models of the human anatomy and physiology …
[HTML][HTML] Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood
PK Eide, E Mariussen, H Uggerud, AH Pripp… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance
could have wide clinical application in predicting excretion of intrathecal drugs and …
could have wide clinical application in predicting excretion of intrathecal drugs and …
Intrathecal 99mTc‐DTPA imaging of molecular passage from lumbar cerebrospinal fluid to brain and periphery in humans
Introduction Cerebrospinal fluid (CSF) molecular exchange with brain interstitial fluid (ISF)
and periphery is implicated in neurological disorders but needs better quantitative clinical …
and periphery is implicated in neurological disorders but needs better quantitative clinical …
Subject-specific studies of CSF bulk flow patterns in the spinal canal: implications for the dispersion of solute particles in intrathecal drug delivery
W Coenen, C Gutiérrez-Montes… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent flow dynamics studies have shown that the
eccentricity of the spinal cord affects the magnitude and characteristics of the slow bulk …
eccentricity of the spinal cord affects the magnitude and characteristics of the slow bulk …
[HTML][HTML] Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders
MH Hovd, E Mariussen, H Uggerud… - Fluids and barriers of the …, 2022 - Springer
Background Quantitative measurements of cerebrospinal fluid to blood clearance has
previously not been established for neurological diseases. Possibly, variability in …
previously not been established for neurological diseases. Possibly, variability in …
Large Intestine 3D Shape Refinement Using Point Diffusion Models for Digital Phantom Generation
Accurate 3D modeling of human organs plays a crucial role in building computational
phantoms for virtual imaging trials. However, generating anatomically plausible …
phantoms for virtual imaging trials. However, generating anatomically plausible …
[BOOK][B] Handbook of Nuclear Medicine and Molecular Imaging for Physicists: Modelling, Dosimetry and Radiation Protection, Volume II
M Ljungberg - 2021 - api.taylorfrancis.com
Mathematical modelling is an important part of nuclear medicine. Therefore, several
chapters of this book have been dedicated towards describing this topic. In these chapters …
chapters of this book have been dedicated towards describing this topic. In these chapters …
Radiation dosimetry in translational intrathecal imaging
JY Hesterman, P Segars, K Palmer… - … Drug Distribution in …, 2021 - spiedigitallibrary.org
Intrathecal (IT) administration is a drug delivery method with great potential for the treatment
of a broad range of neurodegenerative disorders. Imaging is a useful tool for assessing the …
of a broad range of neurodegenerative disorders. Imaging is a useful tool for assessing the …
Human Radiation Dosimetry from Imaging: Guidance for Therapy
RE Wendt III - … in the Management of Leptomeningeal Metastasis, 2022 - Springer
Internal dosimetry of intrathecal radiopharmaceutical therapy employs quantitative imaging
to provide its input data. The MIRD schema is the most widely used approach. It relies upon …
to provide its input data. The MIRD schema is the most widely used approach. It relies upon …
The VIDA software for targeted radionuclide therapy
S Kost, J Hesterman, K Gresco - Monte Carlo Calculations in …, 2022 - iopscience.iop.org
In this chapter, VIDA (Voxel-based Internal Dosimetry Application) 3D image-based
dosimetry technique that employs the Geant4 Monte Carlo toolkit to perform voxel-based …
dosimetry technique that employs the Geant4 Monte Carlo toolkit to perform voxel-based …