Positron emission tomography molecular imaging‐based cancer phenotyping

C Jin, X Luo, X Li, R Zhou, Y Zhong, Z Xu, C Cui… - Cancer, 2022 - Wiley Online Library
During the past several decades, numerous studies have provided insights into biological
characteristics of cancer cells and identified various hallmarks of cancer acquired in the …

[HTML][HTML] Advancements in PARP1 targeted nuclear imaging and theranostic probes

R Ambur Sankaranarayanan, S Kossatz… - Journal of Clinical …, 2020 - mdpi.com
The central paradigm of novel therapeutic approaches in cancer therapy is identifying and
targeting molecular biomarkers. One such target is the nuclear DNA repair enzyme Poly …

Copper-Mediated Radiosynthesis of [18F]Rucaparib

Z Chen, G Destro, F Guibbal, CY Chan… - Organic …, 2021 - ACS Publications
The poly (ADP-ribose) polymerase (PARP) inhibitor rucaparib is used in the clinic to treat
BRCA-mutated cancers. Herein, we report two strategies to access the 18F-isotopologue of …